8PBG
Mutant K1556T of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoroorotate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CAD protein | polymer | 362 | 39623.3 | 1 | UniProt (P27708) Pfam (PF01979) | Homo sapiens (human) | |
| 2 | B, D, E, F, G (A) | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
| 3 | C (A) | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 174.1 | 1 | Chemie (FOT) | |||
| 4 | H, I (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | J (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | K (A) | water | water | 18.0 | 388 | Chemie (HOH) |
Sequence modifications
A: 1460 - 1821 (UniProt: P27708)
| PDB | External Database | Details |
|---|---|---|
| Thr 1556 | Lys 1556 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39623.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 558.0 | |
| All* | Total formula weight | 40181.4 |
