8PAS

Crystal structure of MAP4K1 with a SMOL inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Mitogen-activated protein kinase kinase kinase kinase 1	polymer	289	32362.7	2	UniProt (Q92918) Pfam (PF00069) In PDB	Homo sapiens (human)	Hematopoietic progenitor kinase,MAPK/ERK kinase kinase kinase 1,MEK kinase kinase 1,MEKKK 1
2	A, B	4-[2,6-bis(fluoranyl)-4-(3-morpholin-4-ylpropylcarbamoylamino)phenoxy]-~{N}-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-1~{H}-pyrrolo[2,3-b]pyridine-3-carboxamide	non-polymer		570.5	2	Chemie (XOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64725.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1141.1
All*	Total formula weight	65866.4

*Water molecules are not included.