8P8J
Structure of 5D3-Fab and nanobody(Nb96)-bound ABCG2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (B, A) | ATP-binding cassette sub-family G member 2 | polymer | 655 | 72385.9 | 2 | UniProt (Q9UNQ0) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (human) | Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter |
| 2 | B, G (E, C) | 5D3(Fab) light chain variable domain | polymer | 214 | 23594.0 | 2 | Mus musculus | ||
| 3 | C, F (F, D) | 5D3(Fab) heavy chain variable domain | polymer | 221 | 23843.6 | 2 | Mus musculus | ||
| 4 | E (Z) | Nanobody | polymer | 125 | 13703.1 | 1 | Lama glama | ||
| 5 | H, I (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 253350.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 253792.6 |
