8P7G
Structural characterization of PHOX2B and its DNA interactions shed lights into the molecular basis of the + 7Ala variant pathogenicity in CCHS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Paired mesoderm homeobox protein 2B | polymer | 63 | 7741.8 | 1 | UniProt (Q99453) Pfam (PF00046) In PDB | Homo sapiens (human) | Neuroblastoma Phox,NBPhox,PHOX2B homeodomain protein,Paired-like homeobox 2B |
Sequence modifications
A: 3 - 63 (UniProt: Q99453)
PDB | External Database | Details |
---|---|---|
Ala 1 | - | expression tag |
Ser 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 7741.8 | |
All* | Total formula weight | 7741.8 |