8P5W
Single particle cryo-EM structure of homohexameric 2-oxoglutarate dehydrogenase OdhA from Corynebacterium glutamicum following reaction with the 2-oxoglutarate analogue succinyl phosphonate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 2-oxoglutarate dehydrogenase E1/E2 component | polymer | 1223 | 134972.1 | 6 | UniProt (Q8NRC3) Pfam (PF16078) Pfam (PF00198) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | Corynebacterium glutamicum ATCC 13032 | ODH E1/E2 component |
| 2 | G, J, M, P, S... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 3 | H, K, N, Q, T... (A, B, C, D, E...) | ACETYL COENZYME *A | non-polymer | 809.6 | 6 | Chemie (ACO) | |||
| 4 | I, L, O, R, U... (A, B, C, D, E...) | (4~{S})-4-[(2~{R})-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-2~{H}-1,3-thiazol-2-yl]-4-oxidanyl-4-phosphono-butanoic acid | non-polymer | 608.4 | 6 | Chemie (QSP) |
Sequence modifications
A, B, C, D, E, F: 1 - 1221 (UniProt: Q8NRC3)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 809832.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 8653.6 | |
| All* | Total formula weight | 818486.1 |
