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8P4C

Structural insights into human co-transcriptional capping - structure 3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1970217450.11UniProt (P11414)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Sus scrofa (pig)
2B
(M)
mRNA-capping enzymepolymer59768655.71UniProt (O60942)
Pfam (PF00782)
Pfam (PF01331)
Pfam (PF03919)
Homo sapiens (human)HCAP1,HCE
3C
(N)
DNA (32-MER)polymer329784.31unidentified
4D
(T)
DNA (41-MER)polymer4112712.21unidentified
5E
(B)
DNA-directed RNA polymerase subunit betapolymer1174134041.41UniProt (I3LGP4)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Sus scrofa (pig)
6F
(C)
DNA-directed RNA polymerase II subunit RPB3polymer27531439.11UniProt (I3LCH3)
Pfam (PF01193)
Pfam (PF01000)
Sus scrofa (pig)
7G
(E)
DNA-directed RNA polymerase II subunit Epolymer21024644.31UniProt (I3LSI7)
Pfam (PF03871)
Pfam (PF01191)
Sus scrofa (pig)RPB5 homolog
8H
(F)
DNA-directed RNA polymerase II subunit Fpolymer12714477.01UniProt (F1SKN8)
Pfam (PF01192)
UniProt (by SIFTS) (A0A4X1VEK9)
Sus scrofa (pig)DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog
9I
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer15017162.31UniProt (I3LCB2)
Pfam (PF03870)
Sus scrofa (pig)
10J
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12514541.21UniProt (P60899)
Pfam (PF02150)
Pfam (PF01096)
Sus scrofa (pig)RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
11K
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer677655.11UniProt (A0A4X1VYD0)
Pfam (PF01194)
UniProt (by SIFTS) (A0A8W4F9W9)
Sus scrofa (pig)
12L
(K)
DNA-directed RNA polymerase II subunit RPB11-apolymer11713310.31UniProt (F1RKE4)
Pfam (PF13656)
Sus scrofa (pig)
13M
(L)
RNA polymerase II subunit Kpolymer587018.21UniProt (I3LN51)
Pfam (PF03604)
UniProt (by SIFTS) (A0A4X1TRS6)
Sus scrofa (pig)
14N
(P)
RNA (5'-R(P*CP*GP*GP*AP*GP*AP*GP*GP*GP*AP*AP*CP*CP*CP*AP*CP*U)-3')polymer175504.41unidentified
15O
(D)
RNA polymerase II subunit Dpolymer14216331.31UniProt (A0A287ADR4)
Pfam (PF03874)
UniProt (by SIFTS) (A0A4X1VM56)
Sus scrofa (pig)
16P
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17219314.31UniProt (A0A4X1VKG7)
Pfam (PF03876)
Pfam (PF00575)
Sus scrofa (pig)
17Q
(Y)
Transcription elongation factor SPT4polymer11713210.21UniProt (P63272)
Pfam (PF06093)
Homo sapiens (human)hSPT4,DRB sensitivity-inducing factor 14 kDa subunit,DSIF p14,DRB sensitivity-inducing factor small subunit,DSIF small subunit
18R
(Z)
Transcription elongation factor SPT5polymer1087121145.51UniProt (O00267)
Pfam (PF11942)
Pfam (PF03439)
Pfam (PF00467)
Homo sapiens (human)hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein
19S, T, V
(A, Y)
ZINC IONnon-polymer65.43Chemie (ZN)
20U
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight748396.8
Non-Polymers*Number of molecules4
Total formula weight220.5
All*Total formula weight748617.4
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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