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8P4C

Structural insights into human co-transcriptional capping - structure 3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1970217450.11UniProt (P11414)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
UniProt (by SIFTS) (A0A8D1DPV6)
Sus scrofa (pig)
2B
(M)
mRNA-capping enzymepolymer59768655.71UniProt (O60942)
Pfam (PF00782)
Pfam (PF01331)
Pfam (PF03919)
Homo sapiens (human)HCAP1,HCE
3C
(N)
DNA (32-MER)polymer329784.31unidentified
4D
(T)
DNA (41-MER)polymer4112712.21unidentified
5E
(B)
DNA-directed RNA polymerase subunit betapolymer1174134041.41UniProt (I3LGP4)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Sus scrofa (pig)
6F
(C)
DNA-directed RNA polymerase II subunit RPB3polymer27531439.11UniProt (I3LCH3)
Pfam (PF01193)
Pfam (PF01000)
Sus scrofa (pig)
7G
(E)
DNA-directed RNA polymerase II subunit Epolymer21024644.31UniProt (I3LSI7)
Pfam (PF03871)
Pfam (PF01191)
Sus scrofa (pig)RPB5 homolog
8H
(F)
DNA-directed RNA polymerase II subunit Fpolymer12714477.01UniProt (F1SKN8)
Pfam (PF01192)
UniProt (by SIFTS) (A0A4X1VEK9)
Sus scrofa (pig)DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog
9I
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer15017162.31UniProt (I3LCB2)
Pfam (PF03870)
Sus scrofa (pig)
10J
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12514541.21UniProt (P60899)
Pfam (PF02150)
Pfam (PF01096)
Sus scrofa (pig)RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
11K
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer677655.11UniProt (A0A4X1VYD0)
Pfam (PF01194)
UniProt (by SIFTS) (A0A8W4F9W9)
Sus scrofa (pig)
12L
(K)
DNA-directed RNA polymerase II subunit RPB11-apolymer11713310.31UniProt (F1RKE4)
Pfam (PF13656)
Sus scrofa (pig)
13M
(L)
RNA polymerase II subunit Kpolymer587018.21UniProt (I3LN51)
Pfam (PF03604)
UniProt (by SIFTS) (A0A4X1TRS6)
Sus scrofa (pig)
14N
(P)
RNA (5'-R(P*CP*GP*GP*AP*GP*AP*GP*GP*GP*AP*AP*CP*CP*CP*AP*CP*U)-3')polymer175504.41unidentified
15O
(D)
RNA polymerase II subunit Dpolymer14216331.31UniProt (A0A287ADR4)
Pfam (PF03874)
UniProt (by SIFTS) (A0A4X1VM56)
Sus scrofa (pig)
16P
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17219314.31UniProt (A0A4X1VKG7)
Pfam (PF03876)
Pfam (PF00575)
Sus scrofa (pig)
17Q
(Y)
Transcription elongation factor SPT4polymer11713210.21UniProt (P63272)
Pfam (PF06093)
Homo sapiens (human)hSPT4,DRB sensitivity-inducing factor 14 kDa subunit,DSIF p14,DRB sensitivity-inducing factor small subunit,DSIF small subunit
18R
(Z)
Transcription elongation factor SPT5polymer1087121145.51UniProt (O00267)
Pfam (PF11942)
Pfam (PF03439)
Pfam (PF00467)
Homo sapiens (human)hSPT5,DRB sensitivity-inducing factor 160 kDa subunit,DSIF p160,DRB sensitivity-inducing factor large subunit,DSIF large subunit,Tat-cotransactivator 1 protein,Tat-CT1 protein
19S, T, V
(A, Y)
ZINC IONnon-polymer65.43Chemie (ZN)
20U
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains18
Total formula weight748396.8
Non-Polymers*Number of molecules4
Total formula weight220.5
All*Total formula weight748617.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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