8P4A
Structural insights into human co-transcriptional capping - structure 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-directed RNA polymerase subunit | polymer | 1984 | 218889.5 | 1 | UniProt (A0A7M4DUC2) Pfam (PF04997) Pfam (PF05001) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) Pfam (PF04992) Pfam (PF04990) In PDB | Sus scrofa (pig) | |
| 2 | P | RNA (5'-R(P*AP*AP*AP*AP*CP*CP*CP*AP*GP*GP*GP*AP*AP*CP*CP*CP*AP*CP*U)-3') | polymer | 19 | 6066.7 | 1 | unidentified | ||
| 3 | B | DNA-directed RNA polymerase subunit beta | polymer | 1174 | 134041.4 | 1 | UniProt (I3LGP4) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) In PDB | Sus scrofa (pig) | |
| 4 | C | DNA-directed RNA polymerase II subunit RPB3 | polymer | 275 | 31439.1 | 1 | UniProt (I3LCH3) Pfam (PF01193) Pfam (PF01000) In PDB | Sus scrofa (pig) | |
| 5 | D | RNA polymerase II subunit D | polymer | 142 | 16331.3 | 1 | UniProt (A0A287ADR4) Pfam (PF03874) UniProt (by SIFTS) (A0A4X1VM56) In PDB | Sus scrofa (pig) | |
| 6 | E | DNA-directed RNA polymerase II subunit E | polymer | 210 | 24644.3 | 1 | UniProt (I3LSI7) Pfam (PF03871) Pfam (PF01191) In PDB | Sus scrofa (pig) | RPB5 homolog |
| 7 | F | DNA-directed RNA polymerase II subunit F | polymer | 127 | 14477.0 | 1 | UniProt (F1SKN8) Pfam (PF01192) UniProt (by SIFTS) (A0A4X1VEK9) In PDB | Sus scrofa (pig) | DNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog |
| 8 | G | DNA-directed RNA polymerase II subunit RPB7 | polymer | 172 | 19314.3 | 1 | UniProt (A0A4X1VKG7) Pfam (PF03876) Pfam (PF00575) In PDB | Sus scrofa (pig) | |
| 9 | H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | polymer | 150 | 17162.3 | 1 | UniProt (I3LCB2) Pfam (PF03870) In PDB | Sus scrofa (pig) | |
| 10 | I | DNA-directed RNA polymerase II subunit RPB9 | polymer | 125 | 14541.2 | 1 | UniProt (P60899) Pfam (PF02150) Pfam (PF01096) In PDB | Sus scrofa (pig) | RNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5 |
| 11 | J | DNA-directed RNA polymerases I, II, and III subunit RPABC5 | polymer | 67 | 7655.1 | 1 | UniProt (A0A4X1VYD0) Pfam (PF01194) UniProt (by SIFTS) (A0A8W4F9W9) In PDB | Sus scrofa (pig) | |
| 12 | K | DNA-directed RNA polymerase II subunit RPB11-a | polymer | 117 | 13310.3 | 1 | UniProt (F1RKE4) Pfam (PF13656) In PDB | Sus scrofa (pig) | |
| 13 | L | RNA polymerase II subunit K | polymer | 58 | 7018.2 | 1 | UniProt (I3LN51) Pfam (PF03604) UniProt (by SIFTS) (A0A4X1TRS6) In PDB | Sus scrofa (pig) | |
| 14 | N | DNA (29-MER) | polymer | 29 | 8861.7 | 1 | unidentified | ||
| 15 | T | DNA (38-MER) | polymer | 38 | 11780.6 | 1 | unidentified | ||
| 16 | M | mRNA-capping enzyme | polymer | 597 | 68639.6 | 1 | UniProt (O60942) Pfam (PF00782) Pfam (PF01331) Pfam (PF03919) In PDB | Homo sapiens (human) | HCAP1,HCE |
| 17 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 18 | A, B, C, I, J... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) |
Sequence modifications
M: 1 - 597 (UniProt: O60942)
| PDB | External Database | Details |
|---|---|---|
| Ser 126 | Cys 126 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 614172.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 614720.3 |
