8P3Q
Homomeric GluA2 flip R/G-unedited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 883 | 98908.0 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, F, G, H (E, F, G, H) | Voltage-dependent calcium channel gamma-2 subunit | polymer | 323 | 35938.7 | 4 | UniProt (Q71RJ2) Pfam (PF00822) | Rattus norvegicus (Norway rat) | Neuronal voltage-gated calcium channel gamma-2 subunit,Stargazin,Transmembrane AMPAR regulatory protein gamma-2,TARP gamma-2 |
| 3 | I, L, P, Q, T... (A, B, C, D, F...) | PALMITIC ACID | non-polymer | 256.4 | 7 | Chemie (PLM) | |||
| 4 | J, M, O, R (A, B, C, D) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 4 | Chemie (OLC) | |||
| 5 | K, N, S, W, X (A, B, D, G) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 5 | Chemie (POV) | |||
| 6 | AA, BA, CA, Y, Z (D, F, G, A, C) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -20 - 862 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Ala 231 | Phe 252 | engineered mutation |
| Arg 586 | Gln 607 | variant |
| Arg 743 | Gly 764 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 539386.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 7021.5 | |
| All* | Total formula weight | 546408.4 |
