8P2Z

Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Processed angiotensin-converting enzyme 2	polymer	812	93425.6	1	UniProt (Q9BYF1) Pfam (PF01401) Pfam (PF16959) In PDB	Homo sapiens (human)
2	C	Sodium- and chloride-dependent transporter XTRP3	polymer	641	71376.3	1	UniProt (Q9NP91) Pfam (PF00209) In PDB	Homo sapiens (human)	Sodium/imino-acid transporter 1,Solute carrier family 6 member 20,Transporter rB21A homolog
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	C	(2S)-piperidine-2-carboxylic acid	non-polymer		129.2	1	Chemie (YCP)
5	C	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)

Sequence modifications

A: -6 - 805 (UniProt: Q9BYF1)

PDB	External Database	Details
Asp 11	-	insertion
Tyr 12	-	insertion
Lys 13	-	insertion
Asp 14	-	insertion
Asp 15	-	insertion
Asp 16	-	insertion
Asp 17	-	insertion
Lys 18	Gln 18	conflict

C: 1 - 592 (UniProt: Q9NP91)

PDB	External Database	Details
Ala 593	-	expression tag
Glu 594	-	expression tag
Asn 595	-	expression tag
Leu 596	-	expression tag
Tyr 597	-	expression tag
Phe 598	-	expression tag
Gln 599	-	expression tag
Ser 600	-	expression tag
His 601	-	expression tag
His 602	-	expression tag
His 603	-	expression tag
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
Gly 611	-	expression tag
Ser 612	-	expression tag
Ala 613	-	expression tag
Trp 614	-	expression tag
Ser 615	-	expression tag
His 616	-	expression tag
Pro 617	-	expression tag
Gln 618	-	expression tag
Phe 619	-	expression tag
Glu 620	-	expression tag
Lys 621	-	expression tag
Gly 622	-	expression tag
Gly 623	-	expression tag
Gly 624	-	expression tag
Ser 625	-	expression tag
Gly 626	-	expression tag
Gly 627	-	expression tag
Gly 628	-	expression tag
Ser 629	-	expression tag
Gly 630	-	expression tag
Gly 631	-	expression tag
Ser 632	-	expression tag
Ala 633	-	expression tag
Trp 634	-	expression tag
Ser 635	-	expression tag
His 636	-	expression tag
Pro 637	-	expression tag
Gln 638	-	expression tag
Phe 639	-	expression tag
Glu 640	-	expression tag
Lys 641	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	164801.8
Non-Polymers*	Number of molecules	4
	Total formula weight	607.0
All*	Total formula weight	165408.9

*Water molecules are not included.