8P2K
Ternary complex of translating ribosome, NAC and METAP1
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B5 | 28S rRNA | polymer | 4808 | 1557519.5 | 1 | Oryctolagus cuniculus (rabbit) | ||
2 | B7 | 5S rRNA | polymer | 120 | 38691.9 | 1 | GenBank (4CXE_4) | Oryctolagus cuniculus (rabbit) | |
3 | B8 | 5.8S rRNA | polymer | 158 | 50809.0 | 1 | GenBank (GBCN01009604.1) | Oryctolagus cuniculus (rabbit) | |
4 | BA | 60S ribosomal protein L8 | polymer | 257 | 28103.9 | 1 | UniProt (F2X241) Pfam (PF00181) Pfam (PF03947) In PDB | Oryctolagus cuniculus (rabbit) | |
5 | BB | Ribosomal protein L3 | polymer | 403 | 46121.0 | 1 | UniProt (G1TL06) Pfam (PF00297) In PDB | Oryctolagus cuniculus (rabbit) | |
6 | BC | 60S ribosomal protein L4 | polymer | 413 | 46430.9 | 1 | UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374) In PDB | Oryctolagus cuniculus (rabbit) | |
7 | BD | Ribosomal protein L5 eukaryotic C-terminal domain-containing protein | polymer | 297 | 34509.9 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) In PDB | Oryctolagus cuniculus (rabbit) | |
8 | BE | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) In PDB | Oryctolagus cuniculus (rabbit) | |
9 | BF | Ribosomal Protein uL30 | polymer | 247 | 29201.8 | 1 | UniProt (G1TUB1) Pfam (PF08079) Pfam (PF00327) In PDB | Oryctolagus cuniculus (rabbit) | |
10 | BG | 60S ribosomal protein L7a | polymer | 266 | 30061.8 | 1 | UniProt (P62424) Pfam (PF01248) In PDB | Oryctolagus cuniculus (rabbit) | Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3 |
11 | BH | 60S ribosomal protein L9 | polymer | 192 | 21871.4 | 1 | UniProt (G1SWI6) Pfam (PF00347) In PDB | Oryctolagus cuniculus (rabbit) | |
12 | BI | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) In PDB | Oryctolagus cuniculus (rabbit) | Ribosomal protein L10 |
13 | BJ | 60S ribosomal protein L11 | polymer | 178 | 20288.5 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) In PDB | Oryctolagus cuniculus (rabbit) | |
14 | BK | Glucose-6-phosphate isomerase | polymer | 65 | 7967.2 | 1 | UniProt (P06744) In PDB | Oryctolagus cuniculus (rabbit) | GPI,Autocrine motility factor,AMF,Neuroleukin,NLK,Phosphoglucose isomerase,PGI,Phosphohexose isomerase,PHI,Sperm antigen 36,SA-36 |
15 | BL | 60S ribosomal protein L13 | polymer | 211 | 24331.7 | 1 | UniProt (G1TKB3) Pfam (PF01294) In PDB | Oryctolagus cuniculus (rabbit) | L13 |
16 | BM | 60S ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) In PDB | Oryctolagus cuniculus (rabbit) | |
17 | BN | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) In PDB | Oryctolagus cuniculus (rabbit) | |
18 | BO | 60S ribosomal protein L13a | polymer | 203 | 23533.3 | 1 | UniProt (A0A0N8ETI8) Pfam (PF00572) In PDB | Oryctolagus cuniculus (rabbit) | |
19 | BP | uL22 | polymer | 184 | 21444.2 | 1 | UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6) In PDB | Oryctolagus cuniculus (rabbit) | |
20 | BQ | eL18 | polymer | 188 | 21699.7 | 1 | UniProt (F6QKI9) Pfam (PF17135) In PDB | Oryctolagus cuniculus (rabbit) | |
21 | BR | Ribosomal protein L19 | polymer | 196 | 23535.3 | 1 | UniProt (G1TYL6) Pfam (PF01280) In PDB | Oryctolagus cuniculus (rabbit) | |
22 | BS | 60S ribosomal protein L18a | polymer | 176 | 20749.4 | 1 | UniProt (A0A1Z5LHJ5) Pfam (PF01775) In PDB | Oryctolagus cuniculus (rabbit) | |
23 | BT | 60S ribosomal protein L21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) In PDB | Oryctolagus cuniculus (rabbit) | eL21 |
24 | BU | 60S ribosomal protein L22 | polymer | 128 | 14756.9 | 1 | UniProt (G1TSG1) Pfam (PF01776) In PDB | Oryctolagus cuniculus (rabbit) | |
25 | BV | Ribosomal protein L23 | polymer | 140 | 14892.5 | 1 | UniProt (G1T6D1) Pfam (PF00238) In PDB | Oryctolagus cuniculus (rabbit) | |
26 | BW | Ribosomal protein L24 | polymer | 157 | 17825.1 | 1 | UniProt (G1SE28) Pfam (PF01246) In PDB | Oryctolagus cuniculus (rabbit) | eL24 |
27 | BX | Ribosomal_L23eN domain-containing protein | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) In PDB | Oryctolagus cuniculus (rabbit) | uL23 |
28 | BY | Ribosomal protein L26 | polymer | 145 | 17303.4 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) In PDB | Oryctolagus cuniculus (rabbit) | |
29 | BZ | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) In PDB | Oryctolagus cuniculus (rabbit) | |
30 | Ba | 60S ribosomal protein L27a | polymer | 148 | 16635.6 | 1 | UniProt (G1SNY0) Pfam (PF00828) In PDB | Oryctolagus cuniculus (rabbit) | |
31 | Bb | 60S ribosomal protein L29 | polymer | 245 | 26721.7 | 1 | UniProt (G1SGR6) Pfam (PF01779) In PDB | Oryctolagus cuniculus (rabbit) | |
32 | Bc | 60S ribosomal protein L30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) In PDB | Oryctolagus cuniculus (rabbit) | eL30 |
33 | Bd | 60S ribosomal protein L31 | polymer | 125 | 14494.9 | 1 | UniProt (G1SHG0) Pfam (PF01198) In PDB | Oryctolagus cuniculus (rabbit) | eL31 |
34 | Be | Ribosomal protein L32 | polymer | 135 | 15898.9 | 1 | UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) In PDB | Oryctolagus cuniculus (rabbit) | eL32 |
35 | Bf | 60S ribosomal protein L35a | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) In PDB | Oryctolagus cuniculus (rabbit) | eL33 |
36 | Bg | 60S ribosomal protein L34 | polymer | 117 | 13326.1 | 1 | UniProt (G1TXG5) Pfam (PF01199) In PDB | Oryctolagus cuniculus (rabbit) | |
37 | Bh | 60S ribosomal protein L35 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) In PDB | Oryctolagus cuniculus (rabbit) | uL29 |
38 | Bi | 60S ribosomal protein L36 | polymer | 105 | 12263.8 | 1 | UniProt (G1TTQ5) Pfam (PF01158) In PDB | Oryctolagus cuniculus (rabbit) | |
39 | Bj | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) In PDB | Oryctolagus cuniculus (rabbit) | |
40 | Bk | 60S ribosomal protein L38 | polymer | 70 | 8238.9 | 1 | UniProt (G1U001) Pfam (PF01781) In PDB | Oryctolagus cuniculus (rabbit) | eL38 |
41 | Bl | 60S ribosomal protein L39-like | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) In PDB | Oryctolagus cuniculus (rabbit) | eL39 |
42 | Bm | Ubiquitin-60S ribosomal protein L40 | polymer | 128 | 14800.5 | 1 | UniProt (A0A2I3MBB6) Pfam (PF00240) Pfam (PF01020) In PDB | Oryctolagus cuniculus (rabbit) | |
43 | Bo | eL42 | polymer | 106 | 12490.0 | 1 | UniProt (G1U344) Pfam (PF00935) UniProt (by SIFTS) (G1T040) In PDB | Oryctolagus cuniculus (rabbit) | |
44 | Bp | 60S ribosomal protein L37a | polymer | 92 | 10299.4 | 1 | UniProt (G1SY53) Pfam (PF01780) In PDB | Oryctolagus cuniculus (rabbit) | eL43 |
45 | Br | 60S ribosomal protein L28 | polymer | 137 | 15844.7 | 1 | UniProt (G1U7L1) Pfam (PF01778) In PDB | Oryctolagus cuniculus (rabbit) | |
46 | Bs | 60S acidic ribosomal protein P0 | polymer | 318 | 34380.5 | 1 | UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) In PDB | Oryctolagus cuniculus (rabbit) | uL10 |
47 | Bt | 60S ribosomal protein L12 | polymer | 165 | 17847.6 | 1 | UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298) In PDB | Oryctolagus cuniculus (rabbit) | |
48 | Bv | Ribosomal protein uL1 | polymer | 217 | 24875.4 | 1 | UniProt (G1SKZ8) Pfam (PF00687) In PDB | Oryctolagus cuniculus (rabbit) | |
49 | MA | Methionine aminopeptidase 1 | polymer | 386 | 43274.2 | 1 | UniProt (P53582) Pfam (PF15801) Pfam (PF00557) In PDB | Homo sapiens (human) | MAP 1,MetAP 1,Peptidase M 1 |
50 | Na | Nascent polypeptide-associated complex subunit alpha | polymer | 215 | 23406.8 | 1 | UniProt (Q13765) Pfam (PF01849) Pfam (PF19026) In PDB | Homo sapiens (human) | NAC-alpha,Alpha-NAC |
51 | Nb | Transcription factor BTF3 | polymer | 132 | 14493.8 | 1 | UniProt (A0A7I2YQL2) Pfam (PF01849) In PDB | Homo sapiens (human) | |
52 | A2 | 18s rRNA | polymer | 1870 | 603928.3 | 1 | GenBank (GBCT01000564.1) | Oryctolagus cuniculus (rabbit) | |
53 | AA | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) In PDB | Oryctolagus cuniculus (rabbit) | |
54 | AB | 40S ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) In PDB | Oryctolagus cuniculus (rabbit) | |
55 | AC | Ribosomal protein S27a | polymer | 156 | 18004.0 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) In PDB | Oryctolagus cuniculus (rabbit) | |
56 | AD | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB | Oryctolagus cuniculus (rabbit) | |
57 | AE | eS26 | polymer | 115 | 13047.5 | 1 | UniProt (A0A2K5LQY6) Pfam (PF01283) In PDB | Oryctolagus cuniculus (rabbit) | |
58 | AF | RACK1 | polymer | 317 | 35115.7 | 1 | UniProt (G1SJB4) Pfam (PF00400) In PDB | Oryctolagus cuniculus (rabbit) | WD_REPEATS_REGION domain-containing protein |
59 | AG | 40S ribosomal protein S29 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) In PDB | Oryctolagus cuniculus (rabbit) | uS14 |
60 | AI | E-site tRNA | polymer | 76 | 15209.5 | 1 | Oryctolagus cuniculus | ||
61 | AT | P-site Val-tRNA | polymer | 76 | 24451.6 | 1 | Oryctolagus cuniculus | ||
62 | AZ | 40S ribosomal protein SA | polymer | 295 | 32970.0 | 1 | UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB | Oryctolagus cuniculus (rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
63 | Aa | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 1 | UniProt (G1SS70) Pfam (PF01015) In PDB | Oryctolagus cuniculus (rabbit) | RPS3A |
64 | Ab | 40S ribosomal protein S2 | polymer | 293 | 31285.4 | 1 | UniProt (O18789) Pfam (PF00333) Pfam (PF03719) In PDB | Oryctolagus cuniculus (rabbit) | |
65 | Ac | 40S ribosomal protein S3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB | Oryctolagus cuniculus (rabbit) | uS3 |
66 | Ad | 40S ribosomal protein S4 | polymer | 263 | 29654.9 | 1 | UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB | Oryctolagus cuniculus (rabbit) | |
67 | Ae | Ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) In PDB | Oryctolagus cuniculus (rabbit) | |
68 | Af | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 1 | UniProt (G1TM55) Pfam (PF01092) In PDB | Oryctolagus cuniculus (rabbit) | |
69 | Ag | 40S ribosomal protein S7 | polymer | 432 | 47356.2 | 1 | UniProt (G1SVB0) In PDB | Oryctolagus cuniculus (rabbit) | |
70 | Ah | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 1 | UniProt (G1TJW1) Pfam (PF01201) In PDB | Oryctolagus cuniculus (rabbit) | |
71 | Ai | 40S ribosomal protein S9 | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB | Oryctolagus cuniculus (rabbit) | |
72 | Aj | S10_plectin domain-containing protein | polymer | 165 | 18933.8 | 1 | UniProt (G1TPV3) Pfam (PF03501) In PDB | Oryctolagus cuniculus (rabbit) | eS10 |
73 | Ak | 40S ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB | Oryctolagus cuniculus (rabbit) | |
74 | Al | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) In PDB | Oryctolagus cuniculus (rabbit) | |
75 | Am | 40S ribosomal protein S13 | polymer | 151 | 17259.4 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) In PDB | Oryctolagus cuniculus (rabbit) | uS15 |
76 | An | 40S ribosomal protein S14 | polymer | 151 | 16316.8 | 1 | UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0) In PDB | Oryctolagus cuniculus (rabbit) | |
77 | Ao | 40S ribosomal protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) In PDB | Oryctolagus cuniculus (rabbit) | |
78 | Ap | uS9 | polymer | 172 | 19213.5 | 1 | UniProt (G1SGX4) Pfam (PF00380) In PDB | Oryctolagus cuniculus (rabbit) | |
79 | Aq | 40S ribosomal protein eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) In PDB | Oryctolagus cuniculus (rabbit) | |
80 | Ar | 40S ribosomal protein S18 | polymer | 152 | 17801.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) In PDB | Oryctolagus cuniculus (rabbit) | |
81 | As | 40S ribosomal protein S19 | polymer | 145 | 16104.6 | 1 | UniProt (G1TN62) Pfam (PF01090) In PDB | Oryctolagus cuniculus (rabbit) | |
82 | At | 40S ribosomal protein uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) In PDB | Oryctolagus cuniculus (rabbit) | |
83 | Au | 40S ribosomal protein S21 | polymer | 83 | 9181.4 | 1 | UniProt (A0A1Z5KTU7) Pfam (PF01249) In PDB | Oryctolagus cuniculus (rabbit) | |
84 | Av | Ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) In PDB | Oryctolagus cuniculus (rabbit) | |
85 | Aw | 40S ribosomal protein S23 | polymer | 143 | 15860.7 | 1 | UniProt (G1SZ47) Pfam (PF00164) In PDB | Oryctolagus cuniculus (rabbit) | |
86 | Ax | 40S ribosomal protein S24 | polymer | 130 | 15107.9 | 1 | UniProt (G1T3D8) Pfam (PF01282) In PDB | Oryctolagus cuniculus (rabbit) | |
87 | Ay | 40S ribosomal protein S25 | polymer | 124 | 13645.0 | 1 | UniProt (G1TDB3) Pfam (PF03297) In PDB | Oryctolagus cuniculus (rabbit) | |
88 | Az | 60S ribosomal protein L41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) In PDB | Oryctolagus cuniculus (rabbit) | |
89 | B5, Aa, Bv, Ae, AI... | ANY 5'-MONOPHOSPHATE NUCLEOTIDE | non-polymer | 214.1 | 73 | Chemie (N) | |||
90 | B5, A2 | SPERMIDINE | non-polymer | 145.2 | 30 | Chemie (SPD) | |||
91 | B5, A2 | SPERMINE | non-polymer | 202.3 | 3 | Chemie (SPM) | |||
92 | A2, B5, B8, BV, Ba... | MAGNESIUM ION | non-polymer | 24.3 | 420 | Chemie (MG) | |||
93 | Bo, A2, B5, Bb, B8... | UNKNOWN ATOM OR ION | non-polymer | 312 | Chemie (UNX) | ||||
94 | B7 | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
95 | BD | ACETYLAMINO-ACETIC ACID | non-polymer | 117.1 | 1 | Chemie (AAC) | |||
96 | Bp, AC, AE, AG, Bg... | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
97 | water | water | 18.0 | 2117 | Chemie (HOH) |
Sequence modifications
BD: 1 - 297 (UniProt: G1SYJ6)
BF: 1 - 247 (UniProt: G1TUB1)
BG: 1 - 266 (UniProt: P62424)
BK: 1 - 60 (UniProt: P06744)
BL: 1 - 211 (UniProt: G1TKB3)
BO: 1 - 203 (UniProt: A0A0N8ETI8)
BQ: 1 - 188 (UniProt: F6QKI9)
BR: 1 - 196 (UniProt: G1TYL6)
BS: 1 - 176 (UniProt: A0A1Z5LHJ5)
BU: 1 - 128 (UniProt: G1TSG1)
Bk: 1 - 70 (UniProt: G1U001)
Br: 1 - 137 (UniProt: G1U7L1)
MA: 1 - 386 (UniProt: P53582)
A2: 1 - 1870 (GenBank: GBCT01000564.1)
Ab: 1 - 293 (UniProt: O18789)
Ad: 1 - 263 (UniProt: G1TK17)
Ah: 1 - 208 (UniProt: G1TJW1)
An: 1 - 151 (UniProt: G1U472)
As: 1 - 145 (UniProt: G1TN62)
PDB | External Database | Details |
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Unk 2 | Gly 2 | conflict |
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Arg 61 | Gly 61 | conflict |
Arg 93 | Gly 93 | conflict |
Met 131 | Val 131 | conflict |
Ile 153 | Val 153 | conflict |
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Leu 184 | Ile 184 | conflict |
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Met 60 | Val 60 | conflict |
Met 61 | - | expression tag |
Met 62 | - | expression tag |
Met 63 | - | expression tag |
Met 64 | - | expression tag |
Val 65 | - | expression tag |
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Arg 74 | His 74 | conflict |
Arg 190 | His 190 | conflict |
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Leu 174 | Ile 174 | conflict |
Asp 194 | Glu 194 | conflict |
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Arg 134 | Cys 134 | conflict |
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Arg 38 | His 38 | conflict |
Arg 151 | His 151 | conflict |
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Asn 36 | Ile 36 | conflict |
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Gly 32 | Arg 32 | conflict |
Ala 36 | Glu 36 | conflict |
Phe 39 | Ser 39 | conflict |
Gly 54 | Arg 54 | conflict |
Arg 97 | His 97 | conflict |
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Lys 24 | Asn 24 | conflict |
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Arg 103 | His 103 | conflict |
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Asn 220 | Asp 220 | conflict |
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B8n 1249 | C 3623 | conflict |
4ac 1338 | C 3712 | conflict |
4ac 1843 | C 4217 | conflict |
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Ile 33 | Val 33 | conflict |
Ala 101 | Ser 101 | conflict |
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Gly 25 | Ser 25 | conflict |
Arg 51 | Lys 51 | conflict |
Thr 78 | Ala 78 | conflict |
Val 156 | Met 156 | conflict |
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Arg 47 | Gly 47 | conflict |
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5f0 138 | Asp 155 | conflict |
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Gly 119 | Trp 119 | conflict |
Asn 142 | Lys 142 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 88 |
Total formula weight | 3952464.5 | |
Non-Polymers* | Number of molecules | 848 |
Total formula weight | 31966.1 | |
All* | Total formula weight | 3984430.6 |