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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8P2K

Ternary complex of translating ribosome, NAC and METAP1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B5)		28S rRNApolymer48081557519.51Oryctolagus cuniculus (rabbit)
2B
(B7)		5S rRNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
3C
(B8)		5.8S rRNApolymer15850809.01GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
4D
(BA)		60S ribosomal protein L8polymer25728103.91UniProt (F2X241)
Pfam (PF00181)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)
5E
(BB)		Ribosomal protein L3polymer40346121.01UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)
6F
(BC)		60S ribosomal protein L4polymer41346430.91UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)
7G
(BD)		Ribosomal protein L5 eukaryotic C-terminal domain-containing proteinpolymer29734509.91UniProt (G1SYJ6)
Pfam (PF17144)
Pfam (PF14204)
UniProt (by SIFTS) (P19949)		Oryctolagus cuniculus (rabbit)
8H
(BE)		60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
9I
(BF)		Ribosomal Protein uL30polymer24729201.81UniProt (G1TUB1)
Pfam (PF08079)
Pfam (PF00327)
UniProt (by SIFTS) (G1SV32)		Oryctolagus cuniculus (rabbit)
10J
(BG)		60S ribosomal protein L7apolymer26630061.81UniProt (P62424)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
11K
(BH)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
12L
(BI)		60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10
13M
(BJ)		60S ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
14N
(BK)		Glucose-6-phosphate isomerasepolymer657967.21UniProt (P06744)Oryctolagus cuniculus (rabbit)GPI,Autocrine motility factor,AMF,Neuroleukin,NLK,Phosphoglucose isomerase,PGI,Phosphohexose isomerase,PHI,Sperm antigen 36,SA-36
15O
(BL)		60S ribosomal protein L13polymer21124331.71UniProt (G1TKB3)
Pfam (PF01294)		Oryctolagus cuniculus (rabbit)L13
16P
(BM)		60S ribosomal protein L14polymer21823870.51UniProt (G1SZ12)
Pfam (PF01929)		Oryctolagus cuniculus (rabbit)
17Q
(BN)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
18R
(BO)		60S ribosomal protein L13apolymer20323533.31UniProt (A0A0N8ETI8)
Pfam (PF00572)
UniProt (by SIFTS) (G1TVS8)		Oryctolagus cuniculus (rabbit)
19S
(BP)		uL22polymer18421444.21UniProt (G1TVT6)
Pfam (PF00237)
UniProt (by SIFTS) (G1SCJ6)		Oryctolagus cuniculus (rabbit)
20T
(BQ)		eL18polymer18821699.71UniProt (F6QKI9)
Pfam (PF17135)
UniProt (by SIFTS) (G1TFE0)		Oryctolagus cuniculus (rabbit)
21U
(BR)		Ribosomal protein L19polymer19623535.31UniProt (G1TYL6)
Pfam (PF01280)
Pfam (PF25476)		Oryctolagus cuniculus (rabbit)
22V
(BS)		60S ribosomal protein L18apolymer17620749.41UniProt (A0A1Z5LHJ5)
Pfam (PF01775)
UniProt (by SIFTS) (G1TTY7)		Oryctolagus cuniculus (rabbit)
23W
(BT)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
24X
(BU)		60S ribosomal protein L22polymer12814756.91UniProt (G1TSG1)
Pfam (PF01776)		Oryctolagus cuniculus (rabbit)
25Y
(BV)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
26Z
(BW)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)eL24
27AA
(BX)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
28BA
(BY)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
29CA
(BZ)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
30DA
(Ba)		60S ribosomal protein L27apolymer14816635.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)
31EA
(Bb)		60S ribosomal protein L29polymer24526721.71UniProt (G1SGR6)
Pfam (PF01779)		Oryctolagus cuniculus (rabbit)
32FA
(Bc)		60S ribosomal protein L30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)eL30
33GA
(Bd)		60S ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
34HA
(Be)		Ribosomal protein L32polymer13515898.91UniProt (G1U437)
Pfam (PF01655)
UniProt (by SIFTS) (G1TUN8)		Oryctolagus cuniculus (rabbit)eL32
35IA
(Bf)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
36JA
(Bg)		60S ribosomal protein L34polymer11713326.11UniProt (G1TXG5)
Pfam (PF01199)		Oryctolagus cuniculus (rabbit)
37KA
(Bh)		60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
38LA
(Bi)		60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
39MA
(Bj)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
40NA
(Bk)		60S ribosomal protein L38polymer708238.91UniProt (G1U001)
Pfam (PF01781)		Oryctolagus cuniculus (rabbit)eL38
41OA
(Bl)		60S ribosomal protein L39-likepolymer516455.81UniProt (G1TTN1)
Pfam (PF00832)
UniProt (by SIFTS) (G1SYU7)		Oryctolagus cuniculus (rabbit)eL39
42PA
(Bm)		Ubiquitin-60S ribosomal protein L40polymer12814800.51UniProt (A0A2I3MBB6)
Pfam (PF00240)
Pfam (PF01020)		Oryctolagus cuniculus (rabbit)
43QA
(Bo)		eL42polymer10612490.01UniProt (G1U344)
Pfam (PF00935)
UniProt (by SIFTS) (G1T040)		Oryctolagus cuniculus (rabbit)
44RA
(Bp)		60S ribosomal protein L37apolymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)eL43
45SA
(Br)		60S ribosomal protein L28polymer13715844.71UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)
46TA
(Bs)		60S acidic ribosomal protein P0polymer31834380.51UniProt (G1SPK4)
Pfam (PF00466)
Pfam (PF17777)
Pfam (PF00428)		Oryctolagus cuniculus (rabbit)uL10
47UA
(Bt)		60S ribosomal protein L12polymer16517847.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)		Oryctolagus cuniculus (rabbit)
48VA
(Bv)		Ribosomal protein uL1polymer21724875.41UniProt (G1SKZ8)
Pfam (PF00687)		Oryctolagus cuniculus (rabbit)
49WA
(MA)		Methionine aminopeptidase 1polymer38643274.21UniProt (P53582)
Pfam (PF15801)
Pfam (PF00557)		Homo sapiens (human)MAP 1,MetAP 1,Peptidase M 1
50XA
(Na)		Nascent polypeptide-associated complex subunit alphapolymer21523406.81UniProt (Q13765)
Pfam (PF01849)
Pfam (PF19026)		Homo sapiens (human)NAC-alpha,Alpha-NAC
51YA
(Nb)		Transcription factor BTF3polymer13214493.81UniProt (A0A7I2YQL2)
Pfam (PF01849)		Homo sapiens (human)
52ZA
(A2)		18s rRNApolymer1870603928.31GenBank (GBCT01000564.1)Oryctolagus cuniculus (rabbit)
53AB
(AA)		40S ribosomal protein S27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)		Oryctolagus cuniculus (rabbit)
54BB
(AB)		40S ribosomal protein S28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)		Oryctolagus cuniculus (rabbit)
55CB
(AC)		Ribosomal protein S27apolymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)		Oryctolagus cuniculus (rabbit)
56DB
(AD)		40S ribosomal protein S30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)		Oryctolagus cuniculus (rabbit)
57EB
(AE)		eS26polymer11513047.51UniProt (A0A2K5LQY6)
Pfam (PF01283)		Oryctolagus cuniculus (rabbit)
58FB
(AF)		RACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)		Oryctolagus cuniculus (rabbit)WD_REPEATS_REGION domain-containing protein
59GB
(AG)		40S ribosomal protein S29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)		Oryctolagus cuniculus (rabbit)uS14
60HB
(AI)		E-site tRNApolymer7615209.51Oryctolagus cuniculus
61IB
(AT)		P-site Val-tRNApolymer7624451.61Oryctolagus cuniculus
62JB
(AZ)		40S ribosomal protein SApolymer29532970.01UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)		Oryctolagus cuniculus (rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
63KB
(Aa)		40S ribosomal protein S3apolymer26430002.11UniProt (G1SS70)
Pfam (PF01015)		Oryctolagus cuniculus (rabbit)RPS3A
64LB
(Ab)		40S ribosomal protein S2polymer29331285.41UniProt (O18789)
Pfam (PF00333)
Pfam (PF03719)		Oryctolagus cuniculus (rabbit)
65MB
(Ac)		40S ribosomal protein S3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)		Oryctolagus cuniculus (rabbit)uS3
66NB
(Ad)		40S ribosomal protein S4polymer26329654.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)		Oryctolagus cuniculus (rabbit)
67OB
(Ae)		Ribosomal protein S5polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)		Oryctolagus cuniculus (rabbit)
68PB
(Af)		40S ribosomal protein S6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)		Oryctolagus cuniculus (rabbit)
69QB
(Ag)		40S ribosomal protein S7polymer43247356.21UniProt (G1SVB0)
Pfam (PF01251)		Oryctolagus cuniculus (rabbit)
70RB
(Ah)		40S ribosomal protein S8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)		Oryctolagus cuniculus (rabbit)
71SB
(Ai)		40S ribosomal protein S9polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)		Oryctolagus cuniculus (rabbit)
72TB
(Aj)		S10_plectin domain-containing proteinpolymer16518933.81UniProt (G1TPV3)
Pfam (PF03501)
UniProt (by SIFTS) (G1T168)		Oryctolagus cuniculus (rabbit)eS10
73UB
(Ak)		40S ribosomal protein S11polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)		Oryctolagus cuniculus (rabbit)
74VB
(Al)		40S ribosomal protein S12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
75WB
(Am)		40S ribosomal protein S13polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)		Oryctolagus cuniculus (rabbit)uS15
76XB
(An)		40S ribosomal protein S14polymer15116316.81UniProt (G1U472)
Pfam (PF00411)
UniProt (by SIFTS) (G1T1F0)		Oryctolagus cuniculus (rabbit)
77YB
(Ao)		40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)		Oryctolagus cuniculus (rabbit)
78ZB
(Ap)		uS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)		Oryctolagus cuniculus (rabbit)
79AC
(Aq)		40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)		Oryctolagus cuniculus (rabbit)
80BC
(Ar)		40S ribosomal protein S18polymer15217801.81UniProt (G1TPG3)
Pfam (PF00416)		Oryctolagus cuniculus (rabbit)
81CC
(As)		40S ribosomal protein S19polymer14516104.61UniProt (G1TN62)
Pfam (PF01090)		Oryctolagus cuniculus (rabbit)
82DC
(At)		40S ribosomal protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)		Oryctolagus cuniculus (rabbit)
83EC
(Au)		40S ribosomal protein S21polymer839181.41UniProt (A0A1Z5KTU7)Oryctolagus cuniculus (rabbit)
84FC
(Av)		Ribosomal protein S15apolymer13014865.61UniProt (G1TG89)
Pfam (PF00410)		Oryctolagus cuniculus (rabbit)
85GC
(Aw)		40S ribosomal protein S23polymer14315860.71UniProt (G1SZ47)
Pfam (PF00164)		Oryctolagus cuniculus (rabbit)
86HC
(Ax)		40S ribosomal protein S24polymer13015107.91UniProt (G1T3D8)
Pfam (PF01282)
UniProt (by SIFTS) (A0A5F9D2E6)		Oryctolagus cuniculus (rabbit)
87IC
(Ay)		40S ribosomal protein S25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)		Oryctolagus cuniculus (rabbit)
88JC
(Az)		60S ribosomal protein L41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)
89AD, AIA, BD, BIA, CAA...
(B5, Aa, Bv, Ae, AI...)		ANY 5'-MONOPHOSPHATE NUCLEOTIDEnon-polymer214.173Chemie (N)
90AE, BE, ED, FD, GD...
(B5, A2)		SPERMIDINEnon-polymer145.230Chemie (SPD)
PubChem (1102)
91PD, SD, VAA
(B5, A2)		SPERMINEnon-polymer202.33Chemie (SPM)
PubChem (1103)
92ABA, ACA, ADA, AEA, AF...
(A2, B5, B8, BV, Ba...)		MAGNESIUM IONnon-polymer24.3420Chemie (MG)
PubChem (888)
93AAA, AFA, AGA, AHA, AP...
(Bo, A2, B5, Bb, B8...)		UNKNOWN ATOM OR IONnon-polymer312Chemie (UNX)
94EX
(B7)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
PubChem (177679032)
PubChem (135400627)
PubChem (135487750)
PubChem (136088935)
PubChem (136803486)
PubChem (135398633)
PubChem (135544356)
PubChem (135547949)
PubChem (135600366)
PubChem (135749822)
PubChem (136005188)
PubChem (136073923)
PubChem (136240914)
PubChem (136664747)
PubChem (136772743)
PubChem (136772744)
PubChem (136803487)
PubChem (137286749)
PubChem (164715984)
PubChem (171699466)
95OY
(BD)		ACETYLAMINO-ACETIC ACIDnon-polymer117.11Chemie (AAC)
PubChem (10972)
96BAA, EHA, FHA, HHA, IZ...
(Bp, AC, AE, AG, Bg...)		ZINC IONnon-polymer65.48Chemie (ZN)
97AJA, AKA, BJA, BKA, CJA...
(B5, A2, B7, AI, B8...)		waterwater18.02117Chemie (HOH)
Sequence modifications
BD: 1 - 297 (UniProt: G1SYJ6)
PDBExternal DatabaseDetails
Unk 2Gly 2conflict
BF: 1 - 247 (UniProt: G1TUB1)
PDBExternal DatabaseDetails
Arg 61Gly 61conflict
Arg 93Gly 93conflict
Met 131Val 131conflict
Ile 153Val 153conflict
BG: 1 - 266 (UniProt: P62424)
PDBExternal DatabaseDetails
Leu 184Ile 184conflict
BK: 1 - 60 (UniProt: P06744)
PDBExternal DatabaseDetails
Met 60Val 60conflict
Met 61-expression tag
Met 62-expression tag
Met 63-expression tag
Met 64-expression tag
Val 65-expression tag
BL: 1 - 211 (UniProt: G1TKB3)
PDBExternal DatabaseDetails
Arg 74His 74conflict
Arg 190His 190conflict
BO: 1 - 203 (UniProt: A0A0N8ETI8)
PDBExternal DatabaseDetails
Leu 174Ile 174conflict
Asp 194Glu 194conflict
BQ: 1 - 188 (UniProt: F6QKI9)
PDBExternal DatabaseDetails
Arg 134Cys 134conflict
BR: 1 - 196 (UniProt: G1TYL6)
PDBExternal DatabaseDetails
Arg 38His 38conflict
Arg 151His 151conflict
BS: 1 - 176 (UniProt: A0A1Z5LHJ5)
PDBExternal DatabaseDetails
Asn 36Ile 36conflict
BU: 1 - 128 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32conflict
Ala 36Glu 36conflict
Phe 39Ser 39conflict
Gly 54Arg 54conflict
Arg 97His 97conflict
Bk: 1 - 70 (UniProt: G1U001)
PDBExternal DatabaseDetails
Lys 24Asn 24conflict
Br: 1 - 137 (UniProt: G1U7L1)
PDBExternal DatabaseDetails
Arg 103His 103conflict
MA: 1 - 386 (UniProt: P53582)
PDBExternal DatabaseDetails
Asn 220Asp 220conflict
A2: 1 - 1870 (GenBank: GBCT01000564.1)
PDBExternal DatabaseDetails
B8n 1249C 3623conflict
4ac 1338C 3712conflict
4ac 1843C 4217conflict
Ab: 1 - 293 (UniProt: O18789)
PDBExternal DatabaseDetails
Ile 33Val 33conflict
Ala 101Ser 101conflict
Ad: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25conflict
Arg 51Lys 51conflict
Thr 78Ala 78conflict
Val 156Met 156conflict
Ah: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47conflict
An: 1 - 151 (UniProt: G1U472)
PDBExternal DatabaseDetails
5f0 138Asp 155conflict
As: 1 - 145 (UniProt: G1TN62)
PDBExternal DatabaseDetails
Gly 119Trp 119conflict
Asn 142Lys 142conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains88
Total formula weight3952464.5
Non-Polymers*Number of molecules848
Total formula weight31966.1
All*Total formula weight3984430.6
*Water molecules are not included.

253389

PDB entries from 2026-05-13

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