8P2G
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S ribosomal RNA | polymer | 2923 | 946782.7 | 1 | GenBank (CP000253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 2 | B (B) | 5S ribosomal RNA | polymer | 115 | 36974.9 | 1 | GenBank (CP000253.1) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 3 | C (D) | tRNA | polymer | 77 | 24802.8 | 1 | GenBank (1848851804) | Escherichia coli | |
| 4 | D (E) | Elongation factor G | polymer | 693 | 76699.3 | 1 | UniProt (Q2G0N1) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Staphylococcus aureus subsp. aureus NCTC 8325 | EF-G |
| 5 | E (G) | 50S ribosomal protein L2 | polymer | 277 | 30217.2 | 1 | UniProt (P60430) Pfam (PF00181) Pfam (PF03947) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 6 | F (H) | 50S ribosomal protein L3 | polymer | 220 | 23760.3 | 1 | UniProt (Q2FW06) Pfam (PF00297) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 7 | G (I) | 50S ribosomal protein L4 | polymer | 207 | 22495.7 | 1 | UniProt (Q2FW07) Pfam (PF00573) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 8 | H (J) | 50S ribosomal protein L5 | polymer | 179 | 20296.6 | 1 | UniProt (Q2FW18) Pfam (PF00281) Pfam (PF00673) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 9 | I (K) | 50S ribosomal protein L6 | polymer | 178 | 19818.6 | 1 | UniProt (Q2FW21) Pfam (PF00347) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 10 | J (M) | 50S ribosomal protein L13 | polymer | 145 | 16359.4 | 1 | UniProt (Q2FW38) Pfam (PF00572) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 11 | K (N) | 50S ribosomal protein L14 | polymer | 122 | 13157.3 | 1 | UniProt (Q2FW16) Pfam (PF00238) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 12 | L (O) | 50S ribosomal protein L15 | polymer | 146 | 15628.9 | 1 | UniProt (P0A0F8) Pfam (PF00828) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 13 | M (P) | 50S ribosomal protein L16 | polymer | 144 | 16274.0 | 1 | UniProt (Q2FW13) Pfam (PF00252) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 14 | N (Q) | 50S ribosomal protein L17 | polymer | 122 | 13771.8 | 1 | UniProt (Q2FW33) Pfam (PF01196) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 15 | O (R) | 50S ribosomal protein L18 | polymer | 119 | 13124.1 | 1 | UniProt (Q2FW22) Pfam (PF00861) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 16 | P (S) | 50S ribosomal protein L19 | polymer | 116 | 13392.8 | 1 | UniProt (Q2FZ42) Pfam (PF01245) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 17 | Q (T) | 50S ribosomal protein L20 | polymer | 118 | 13720.3 | 1 | UniProt (Q2FXQ1) Pfam (PF00453) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 18 | R (U) | 50S ribosomal protein L21 | polymer | 102 | 11354.1 | 1 | UniProt (Q2FXS8) Pfam (PF00829) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 19 | S (V) | 50S ribosomal protein L22 | polymer | 117 | 12857.9 | 1 | UniProt (Q2FW11) Pfam (PF00237) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 20 | T (W) | 50S ribosomal protein L23 | polymer | 91 | 10625.4 | 1 | UniProt (Q2FW08) Pfam (PF00276) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 21 | U (X) | 50S ribosomal protein L24 | polymer | 105 | 11561.5 | 1 | UniProt (Q2FW17) Pfam (PF00467) Pfam (PF17136) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 22 | V (Y) | 50S ribosomal protein L25 | polymer | 217 | 23810.6 | 1 | UniProt (Q2G0S0) Pfam (PF01386) Pfam (PF14693) | Staphylococcus aureus subsp. aureus NCTC 8325 | General stress protein CTC |
| 23 | W (Z) | 50S ribosomal protein L27 | polymer | 94 | 10334.8 | 1 | UniProt (Q2FXT0) Pfam (PF01016) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 24 | X (1) | 50S ribosomal protein L28 | polymer | 62 | 6995.3 | 1 | UniProt (Q2FZ60) Pfam (PF00830) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 25 | Y (2) | 50S ribosomal protein L29 | polymer | 69 | 8105.3 | 1 | UniProt (Q2FW14) Pfam (PF00831) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 26 | Z (3) | 50S ribosomal protein L30 | polymer | 59 | 6565.7 | 1 | UniProt (P0A0G2) Pfam (PF00327) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 27 | AA (4) | 50S ribosomal protein L31 type B | polymer | 84 | 9737.9 | 1 | UniProt (Q2FWD8) Pfam (PF01197) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 28 | BA (5) | Large ribosomal subunit protein bL32 | polymer | 57 | 6500.6 | 1 | UniProt (Q2FZF1) Pfam (PF01783) | Staphylococcus aureus subsp. aureus NCTC 8325 | 50S ribosomal protein L32 |
| 29 | CA (6) | Large ribosomal subunit protein bL33A | polymer | 49 | 5944.9 | 1 | UniProt (Q2FYU6) Pfam (PF00471) | Staphylococcus aureus subsp. aureus NCTC 8325 | 50S ribosomal protein L33 1 |
| 30 | DA (7) | 50S ribosomal protein L34 | polymer | 45 | 5454.6 | 1 | UniProt (Q2FUQ0) Pfam (PF00468) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 31 | EA (8) | 50S ribosomal protein L35 | polymer | 66 | 7722.4 | 1 | UniProt (Q2FXQ0) Pfam (PF01632) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 32 | FA (9) | 50S ribosomal protein L36 | polymer | 37 | 4318.4 | 1 | UniProt (Q2FW29) Pfam (PF00444) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 33 | GA (a) | 16S ribosomal RNA | polymer | 1555 | 503117.2 | 1 | GenBank (CP000253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 34 | HA (b) | mRNA | polymer | 24 | 7889.9 | 1 | Escherichia coli | ||
| 35 | IA (c) | 30S ribosomal protein S2 | polymer | 255 | 29136.4 | 1 | UniProt (Q2FZ25) Pfam (PF00318) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 36 | JA (d) | 30S ribosomal protein S3 | polymer | 217 | 24143.9 | 1 | UniProt (Q2FW12) Pfam (PF07650) Pfam (PF00189) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 37 | KA (e) | 30S ribosomal protein S4 | polymer | 200 | 23051.4 | 1 | UniProt (Q2FXK6) Pfam (PF00163) Pfam (PF01479) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 38 | LA (f) | 30S ribosomal protein S5 | polymer | 166 | 17770.5 | 1 | UniProt (Q2FW23) Pfam (PF00333) Pfam (PF03719) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 39 | MA (g) | 30S ribosomal protein S6 | polymer | 98 | 11613.1 | 1 | UniProt (Q2G113) Pfam (PF01250) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 40 | NA (h) | 30S ribosomal protein S7 | polymer | 156 | 17826.6 | 1 | UniProt (P48940) Pfam (PF00177) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 41 | OA (i) | 30S ribosomal protein S8 | polymer | 132 | 14854.3 | 1 | UniProt (Q2FW20) Pfam (PF00410) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 42 | PA (j) | 30S ribosomal protein S9 | polymer | 132 | 14857.0 | 1 | UniProt (Q2FW39) Pfam (PF00380) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 43 | QA (k) | Small ribosomal subunit protein uS10 | polymer | 102 | 11598.5 | 1 | UniProt (A5IV35) Pfam (PF00338) UniProt (by SIFTS) (A0A0D1JTN2) | Staphylococcus aureus subsp. aureus NCTC 8325 | 30S ribosomal protein S10 |
| 44 | RA (l) | 30S ribosomal protein S11 | polymer | 129 | 13908.0 | 1 | UniProt (Q2FW31) Pfam (PF00411) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 45 | SA (m) | 30S ribosomal protein S12 | polymer | 137 | 15320.9 | 1 | UniProt (P0A0H0) Pfam (PF00164) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 46 | TA (n) | 30S ribosomal protein S13 | polymer | 121 | 13747.9 | 1 | UniProt (Q2FW30) Pfam (PF00416) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 47 | UA (o) | 30S ribosomal protein S14 type Z | polymer | 61 | 7317.8 | 1 | UniProt (Q2FW19) Pfam (PF00253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 48 | VA (p) | 30S ribosomal protein S15 | polymer | 89 | 10634.3 | 1 | UniProt (Q2G2Q1) Pfam (PF00312) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 49 | WA (q) | 30S ribosomal protein S16 | polymer | 91 | 10253.9 | 1 | UniProt (Q2FZ45) Pfam (PF00886) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 50 | XA (r) | 30S ribosomal protein S17 | polymer | 87 | 10196.9 | 1 | UniProt (Q2FW15) Pfam (PF00366) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 51 | YA (s) | 30S ribosomal protein S18 | polymer | 80 | 9332.0 | 1 | UniProt (Q2G111) Pfam (PF01084) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 52 | ZA (t) | 30S ribosomal protein S19 | polymer | 92 | 10639.3 | 1 | UniProt (Q2FW10) Pfam (PF00203) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 53 | AB (u) | 30S ribosomal protein S20 | polymer | 83 | 9039.5 | 1 | UniProt (Q2FXY6) Pfam (PF01649) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 54 | AC, AD, AE, AF, AG... (A, a, B, E, G...) | MAGNESIUM ION | non-polymer | 24.3 | 169 | Chemie (MG) | |||
| 55 | DF, EF, FF (A) | SPERMIDINE | non-polymer | 145.2 | 3 | Chemie (SPD) | |||
| 56 | GF (A) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 1 | Chemie (PUT) | |||
| 57 | RG (E) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 58 | TG (E) | 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid | non-polymer | 546.8 | 1 | Chemie (WUX) | |||
| 59 | WH, XG, YG (o, 5, 9) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 60 | AI, BI, CI, DI, EI... (E, G, H, I, M...) | water | water | 18.0 | 3169 | Chemie (HOH) |
Sequence modifications
A: 1 - 2923 (GenBank: CP000253)
5: 1 - 57 (UniProt: Q2FZF1)
| PDB | External Database | Details |
|---|---|---|
| G 48 | A 450786 | conflict |
| U 1584 | A 452322 | conflict |
| G 2261 | A 452999 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Arg 35 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 53 |
| Total formula weight | 2245415.3 | |
| Non-Polymers* | Number of molecules | 178 |
| Total formula weight | 5817.6 | |
| All* | Total formula weight | 2251232.9 |
