8P2F
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | 50S ribosomal protein L28 | polymer | 62 | 6995.3 | 1 | UniProt (Q2FZ60) Pfam (PF00830) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 2 | B (2) | 50S ribosomal protein L29 | polymer | 69 | 8105.3 | 1 | UniProt (Q2FW14) Pfam (PF00831) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 3 | C (3) | 50S ribosomal protein L30 | polymer | 59 | 6565.7 | 1 | UniProt (P0A0G2) Pfam (PF00327) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 4 | D (4) | 50S ribosomal protein L31 type B | polymer | 84 | 9737.9 | 1 | UniProt (Q2FWD8) Pfam (PF01197) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 5 | E (5) | 50S ribosomal protein L32 | polymer | 57 | 6500.6 | 1 | UniProt (Q2FZF1) Pfam (PF01783) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 6 | F (6) | 50S ribosomal protein L33 1 | polymer | 49 | 5944.9 | 1 | UniProt (Q2FYU6) Pfam (PF00471) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 7 | G (7) | 50S ribosomal protein L34 | polymer | 45 | 5454.6 | 1 | UniProt (Q2FUQ0) Pfam (PF00468) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 8 | H (8) | 50S ribosomal protein L35 | polymer | 66 | 7722.4 | 1 | UniProt (Q2FXQ0) Pfam (PF01632) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 9 | I (9) | 50S ribosomal protein L36 | polymer | 37 | 4318.4 | 1 | UniProt (Q2FW29) Pfam (PF00444) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 10 | J (A) | 23S ribosomal RNA | polymer | 2923 | 946782.7 | 1 | GenBank (CP000253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 11 | K (B) | 5S ribosomal RNA | polymer | 115 | 36974.9 | 1 | GenBank (CP000253.1) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 12 | L, N (D, F) | tRNA | polymer | 77 | 24802.8 | 2 | GenBank (1848851804) | Escherichia coli | |
| 13 | M (E) | Elongation factor G | polymer | 693 | 76699.3 | 1 | UniProt (Q2G0N1) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Staphylococcus aureus subsp. aureus NCTC 8325 | EF-G |
| 14 | O (G) | 50S ribosomal protein L2 | polymer | 277 | 30217.2 | 1 | UniProt (P60430) Pfam (PF00181) Pfam (PF03947) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 15 | P (H) | 50S ribosomal protein L3 | polymer | 220 | 23760.3 | 1 | UniProt (Q2FW06) Pfam (PF00297) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 16 | Q (I) | 50S ribosomal protein L4 | polymer | 207 | 22495.7 | 1 | UniProt (Q2FW07) Pfam (PF00573) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 17 | R (J) | 50S ribosomal protein L5 | polymer | 179 | 20296.6 | 1 | UniProt (Q2FW18) Pfam (PF00281) Pfam (PF00673) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 18 | S (K) | 50S ribosomal protein L6 | polymer | 178 | 19818.6 | 1 | UniProt (Q2FW21) Pfam (PF00347) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 19 | T (M) | 50S ribosomal protein L13 | polymer | 145 | 16359.4 | 1 | UniProt (Q2FW38) Pfam (PF00572) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 20 | U (N) | 50S ribosomal protein L14 | polymer | 122 | 13157.3 | 1 | UniProt (Q2FW16) Pfam (PF00238) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 21 | V (O) | 50S ribosomal protein L15 | polymer | 146 | 15628.9 | 1 | UniProt (P0A0F8) Pfam (PF00828) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 22 | W (P) | 50S ribosomal protein L16 | polymer | 144 | 16274.0 | 1 | UniProt (Q2FW13) Pfam (PF00252) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 23 | X (Q) | 50S ribosomal protein L17 | polymer | 122 | 13771.8 | 1 | UniProt (Q2FW33) Pfam (PF01196) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 24 | Y (R) | 50S ribosomal protein L18 | polymer | 119 | 13124.1 | 1 | UniProt (Q2FW22) Pfam (PF00861) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 25 | Z (S) | 50S ribosomal protein L19 | polymer | 116 | 13392.8 | 1 | UniProt (Q2FZ42) Pfam (PF01245) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 26 | AA (T) | 50S ribosomal protein L20 | polymer | 118 | 13720.3 | 1 | UniProt (Q2FXQ1) Pfam (PF00453) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 27 | BA (U) | 50S ribosomal protein L21 | polymer | 102 | 11354.1 | 1 | UniProt (Q2FXS8) Pfam (PF00829) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 28 | CA (V) | 50S ribosomal protein L22 | polymer | 117 | 12857.9 | 1 | UniProt (Q2FW11) Pfam (PF00237) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 29 | DA (W) | 50S ribosomal protein L23 | polymer | 91 | 10625.4 | 1 | UniProt (Q2FW08) Pfam (PF00276) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 30 | EA (X) | 50S ribosomal protein L24 | polymer | 105 | 11561.5 | 1 | UniProt (Q2FW17) Pfam (PF00467) Pfam (PF17136) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 31 | FA (Y) | 50S ribosomal protein L25 | polymer | 217 | 23810.6 | 1 | UniProt (Q2G0S0) Pfam (PF01386) Pfam (PF14693) | Staphylococcus aureus subsp. aureus NCTC 8325 | General stress protein CTC |
| 32 | GA (Z) | 50S ribosomal protein L27 | polymer | 94 | 10334.8 | 1 | UniProt (Q2FXT0) Pfam (PF01016) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 33 | HA (a) | 16S ribosomal RNA | polymer | 1555 | 503117.2 | 1 | GenBank (CP000253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 34 | IA (b) | mRNA | polymer | 24 | 7889.9 | 1 | Escherichia coli | ||
| 35 | JA (c) | 30S ribosomal protein S2 | polymer | 255 | 29136.4 | 1 | UniProt (Q2FZ25) Pfam (PF00318) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 36 | KA (d) | 30S ribosomal protein S3 | polymer | 217 | 24143.9 | 1 | UniProt (Q2FW12) Pfam (PF07650) Pfam (PF00189) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 37 | LA (e) | 30S ribosomal protein S4 | polymer | 200 | 23051.4 | 1 | UniProt (Q2FXK6) Pfam (PF00163) Pfam (PF01479) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 38 | MA (f) | 30S ribosomal protein S5 | polymer | 166 | 17770.5 | 1 | UniProt (Q2FW23) Pfam (PF00333) Pfam (PF03719) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 39 | NA (g) | 30S ribosomal protein S6 | polymer | 98 | 11613.1 | 1 | UniProt (Q2G113) Pfam (PF01250) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 40 | OA (h) | 30S ribosomal protein S7 | polymer | 156 | 17826.6 | 1 | UniProt (P48940) Pfam (PF00177) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 41 | PA (i) | 30S ribosomal protein S8 | polymer | 132 | 14854.3 | 1 | UniProt (Q2FW20) Pfam (PF00410) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 42 | QA (j) | 30S ribosomal protein S9 | polymer | 132 | 14857.0 | 1 | UniProt (Q2FW39) Pfam (PF00380) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 43 | RA (k) | 30S ribosomal protein S10 | polymer | 102 | 11598.5 | 1 | UniProt (A0A0D1JTN2) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 44 | SA (l) | 30S ribosomal protein S11 | polymer | 129 | 13908.0 | 1 | UniProt (Q2FW31) Pfam (PF00411) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 45 | TA (m) | 30S ribosomal protein S12 | polymer | 137 | 15320.9 | 1 | UniProt (P0A0H0) Pfam (PF00164) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 46 | UA (n) | 30S ribosomal protein S13 | polymer | 121 | 13747.9 | 1 | UniProt (Q2FW30) Pfam (PF00416) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 47 | VA (o) | 30S ribosomal protein S14 type Z | polymer | 61 | 7317.8 | 1 | UniProt (Q2FW19) Pfam (PF00253) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 48 | WA (p) | 30S ribosomal protein S15 | polymer | 89 | 10634.3 | 1 | UniProt (Q2G2Q1) Pfam (PF00312) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 49 | XA (q) | 30S ribosomal protein S16 | polymer | 91 | 10253.9 | 1 | UniProt (Q2FZ45) Pfam (PF00886) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 50 | YA (r) | 30S ribosomal protein S17 | polymer | 87 | 10196.9 | 1 | UniProt (Q2FW15) Pfam (PF00366) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 51 | ZA (s) | 30S ribosomal protein S18 | polymer | 80 | 9332.0 | 1 | UniProt (Q2G111) Pfam (PF01084) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 52 | AB (t) | 30S ribosomal protein S19 | polymer | 92 | 10639.3 | 1 | UniProt (Q2FW10) Pfam (PF00203) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 53 | BB (u) | 30S ribosomal protein S20 | polymer | 83 | 9039.5 | 1 | UniProt (Q2FXY6) Pfam (PF01649) | Staphylococcus aureus subsp. aureus NCTC 8325 | |
| 54 | CB, EB, YG (5, 9, o) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 55 | AC, AD, AE, AF, AG... (A, 8, E, F, a) | MAGNESIUM ION | non-polymer | 24.3 | 145 | Chemie (MG) PubChem (888) | |||
| 56 | FB (A) | SPERMIDINE | non-polymer | 145.2 | 1 | Chemie (SPD) PubChem (1102) | |||
| 57 | GB (A) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 1 | Chemie (PUT) PubChem (1045) | |||
| 58 | IG (E) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 59 | KG (E) | 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid | non-polymer | 546.8 | 1 | Chemie (WUX) | |||
| 60 | NG (P) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 61 | AH, BH, CH, DH, EH... (5, 7, 8, 9, A...) | water | water | 18.0 | 1619 | Chemie (HOH) |
Sequence modifications
5: 1 - 57 (UniProt: Q2FZF1)
A: 1 - 2923 (GenBank: CP000253)
| PDB | External Database | Details |
|---|---|---|
| - | Arg 35 | deletion |
| PDB | External Database | Details |
|---|---|---|
| G 48 | A 450786 | conflict |
| U 1584 | A 452322 | conflict |
| G 2261 | A 452999 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 54 |
| Total formula weight | 2270218.1 | |
| Non-Polymers* | Number of molecules | 153 |
| Total formula weight | 4982.9 | |
| All* | Total formula weight | 2275201.0 |
