8P1N

Structure of hantaan orthohantavirus (HTNV) polymerase bound to 5'vRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-directed RNA polymerase L	polymer	2196	251806.0	1	UniProt (P23456) Pfam (PF21991) Pfam (PF12426) Pfam (PF04196)	Hantaan orthohantavirus	Protein L,Large structural protein,RdRp,Replicase,Transcriptase
2	B (B)	RNA (5'-R(P*AP*GP*UP*AP*G)-3')	polymer	17	5404.2	1		Hantaan orthohantavirus

Sequence modifications

A: 1 - 2151 (UniProt: P23456)

PDB	External Database	Details
Met -44	-	initiating methionine
Trp -43	-	expression tag
Ser -42	-	expression tag
His -41	-	expression tag
Pro -40	-	expression tag
Gln -39	-	expression tag
Phe -38	-	expression tag
Glu -37	-	expression tag
Lys -36	-	expression tag
Gly -35	-	expression tag
Gly -34	-	expression tag
Gly -33	-	expression tag
Ser -32	-	expression tag
Gly -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Ser -28	-	expression tag
Gly -27	-	expression tag
Gly -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Ala -23	-	expression tag
Trp -22	-	expression tag
Ser -21	-	expression tag
His -20	-	expression tag
Pro -19	-	expression tag
Gln -18	-	expression tag
Phe -17	-	expression tag
Glu -16	-	expression tag
Lys -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Ala 97	Asp 97	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	257210.3
All*	Total formula weight	257210.3

*Water molecules are not included.