8P14
USP28 USP domain in complex with Vismodegib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ubiquitin carboxyl-terminal hydrolase 28 | polymer | 377 | 44026.0 | 1 | UniProt (Q96RU2) Pfam (PF00443) In PDB | Homo sapiens (human) | Deubiquitinating enzyme 28,Ubiquitin thioesterase 28,Ubiquitin-specific-processing protease 28 |
| 2 | A | 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide | non-polymer | 421.3 | 1 | Chemie (VIS) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 149 - 399 (UniProt: Q96RU2)
A: 406 - 524 (UniProt: Q96RU2)
| PDB | External Database | Details |
|---|---|---|
| Gly 148 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 400 | - | linker |
| Ser 401 | - | linker |
| Gly 402 | - | linker |
| Ser 403 | - | linker |
| Gly 404 | - | linker |
| Ser 405 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44026.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 563.1 | |
| All* | Total formula weight | 44589.1 |
