8P07
Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with 5-((3-(4H-1,2,4-triazol-4-yl)phenyl)amino)-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Casein kinase II subunit alpha | polymer | 338 | 40328.0 | 2 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (human) | CK II alpha |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 3 | A, B | 7-(cyclopropylamino)-5-[[3-(1,2,4-triazol-4-yl)phenyl]amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile | non-polymer | 357.4 | 2 | Chemie (WAP) | |||
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80656.0 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2115.8 | |
| All* | Total formula weight | 82771.7 |
