8P03
48S late-stage initiation complex with m6A mRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | initiator methionylated tRNA | polymer | 75 | 24376.6 | 1 | Oryctolagus cuniculus | ||
| 2 | B (2) | 18S ribosomal RNA | polymer | 1863 | 601015.7 | 1 | Oryctolagus cuniculus | ||
| 3 | C (3) | m6A-methylated mRNA | polymer | 9 | 2882.8 | 1 | Oryctolagus cuniculus | ||
| 4 | D (A) | Eukaryotic translation initiation factor 2 subunit 1 | polymer | 284 | 32792.9 | 1 | UniProt (G1T2G4) Pfam (PF00575) Pfam (PF07541) | Oryctolagus cuniculus (rabbit) | |
| 5 | E (C) | 40S ribosomal protein SA | polymer | 207 | 23273.7 | 1 | UniProt (G1TLT8) Pfam (PF00318) | Oryctolagus cuniculus (rabbit) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40 |
| 6 | F (D) | ribosomal protein eS1 | polymer | 215 | 24944.4 | 1 | UniProt (G1TN72) Pfam (PF01015) | Oryctolagus cuniculus (rabbit) | |
| 7 | G (E) | 40S ribosomal protein S2 | polymer | 270 | 29100.0 | 1 | UniProt (G1TUT9) | Oryctolagus cuniculus (rabbit) | |
| 8 | H (F) | Ribosomal protein S3 | polymer | 227 | 25158.5 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) | Oryctolagus cuniculus (rabbit) | |
| 9 | I (G) | 40S ribosomal protein S4 | polymer | 263 | 29658.9 | 1 | UniProt (G1TK17) Pfam (PF00467) Pfam (PF16121) Pfam (PF08071) Pfam (PF00900) | Oryctolagus cuniculus (rabbit) | |
| 10 | J (H) | Ribosomal protein S5 | polymer | 191 | 21525.9 | 1 | UniProt (U3KMN4) Pfam (PF00177) | Oryctolagus cuniculus (rabbit) | |
| 11 | K (I) | 40S ribosomal protein S6 | polymer | 237 | 27475.5 | 1 | UniProt (A0A5K1UJS7) Pfam (PF01092) | Oryctolagus cuniculus (rabbit) | |
| 12 | L (J) | ribosomal protein eS7 | polymer | 190 | 21716.4 | 1 | UniProt (G1SVB0) | Oryctolagus cuniculus (rabbit) | |
| 13 | M (K) | 40S ribosomal protein S8 | polymer | 206 | 23902.9 | 1 | UniProt (G1TJW1) Pfam (PF01201) | Oryctolagus cuniculus (rabbit) | |
| 14 | N (L) | 40S ribosomal protein S9 | polymer | 194 | 22641.6 | 1 | UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) | Oryctolagus cuniculus (rabbit) | |
| 15 | O (M) | 40S ribosomal protein eS10 | polymer | 98 | 11774.0 | 1 | UniProt (G1TPV3) Pfam (PF03501) | Oryctolagus cuniculus (rabbit) | |
| 16 | P (N) | 40S ribosomal protein S11 | polymer | 158 | 18468.8 | 1 | UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) | Oryctolagus cuniculus (rabbit) | |
| 17 | Q (O) | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (G1SFR8) Pfam (PF01248) | Oryctolagus cuniculus (rabbit) | |
| 18 | R (P) | ribosomal protein uS15 | polymer | 150 | 17128.2 | 1 | UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) | Oryctolagus cuniculus (rabbit) | |
| 19 | S (Q) | 40S ribosomal protein uS11 | polymer | 151 | 16302.8 | 1 | UniProt (G1T1F0) Pfam (PF00411) | Oryctolagus cuniculus (rabbit) | |
| 20 | T (R) | 40S ribosomal protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) | Oryctolagus cuniculus (rabbit) | |
| 21 | U (S) | 40S ribosomal protein uS9 | polymer | 141 | 15975.8 | 1 | UniProt (G1SGX4) Pfam (PF00380) | Oryctolagus cuniculus (rabbit) | |
| 22 | V (T) | 40S ribosomal protein eS17 | polymer | 135 | 15552.1 | 1 | UniProt (G1TU13) Pfam (PF00833) | Oryctolagus cuniculus (rabbit) | |
| 23 | W (U) | 40S ribosomal protein uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) | Oryctolagus cuniculus (rabbit) | |
| 24 | X (V) | 40S ribosomal protein eS19 | polymer | 141 | 15812.3 | 1 | UniProt (G1TN62) Pfam (PF01090) | Oryctolagus cuniculus (rabbit) | |
| 25 | Y (W) | 40S ribosomal protein uS10 | polymer | 119 | 13398.8 | 1 | UniProt (G1SIZ2) Pfam (PF00338) | Oryctolagus cuniculus (rabbit) | |
| 26 | Z (X) | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (Q32PB8) Pfam (PF01249) | Oryctolagus cuniculus (rabbit) | |
| 27 | AA (Y) | Ribosomal protein S15a | polymer | 130 | 14865.6 | 1 | UniProt (G1TG89) Pfam (PF00410) | Oryctolagus cuniculus (rabbit) | |
| 28 | BA (Z) | 40S ribosomal protein S23 | polymer | 143 | 15844.7 | 1 | UniProt (G1SZ47) Pfam (PF00164) | Oryctolagus cuniculus (rabbit) | RPS23 |
| 29 | CA (a) | 40S ribosomal protein S24 | polymer | 133 | 15434.3 | 1 | UniProt (G1TS40) Pfam (PF01282) UniProt (by SIFTS) (A0A5F9D2E6) | Oryctolagus cuniculus (rabbit) | |
| 30 | DA (b) | 40S ribosomal protein S26 | polymer | 115 | 12961.5 | 1 | UniProt (G1TFE8) Pfam (PF01283) | Oryctolagus cuniculus (rabbit) | |
| 31 | EA (c) | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | UniProt (G1TZ76) Pfam (PF01667) | Oryctolagus cuniculus (rabbit) | |
| 32 | FA (d) | 40S ribosomal protein S28 | polymer | 69 | 7855.1 | 1 | UniProt (G1TIB4) Pfam (PF01200) | Oryctolagus cuniculus (rabbit) | |
| 33 | GA (e) | 40S ribosomal protein S29 | polymer | 56 | 6690.8 | 1 | UniProt (G1U7M4) Pfam (PF00253) | Oryctolagus cuniculus (rabbit) | uS14 |
| 34 | HA (f) | ribosomal protein eS31 | polymer | 71 | 8358.9 | 1 | UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) | Oryctolagus cuniculus (rabbit) | |
| 35 | IA (g) | Ribosomal protein RACK1 | polymer | 313 | 34669.1 | 1 | UniProt (G1SJB4) Pfam (PF00400) | Oryctolagus cuniculus (rabbit) | |
| 36 | JA (i) | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) | Oryctolagus cuniculus (rabbit) | |
| 37 | KA (j) | Eukaryotic translation initiation factor 4C | polymer | 111 | 12788.8 | 1 | UniProt (G1SYS4) Pfam (PF01176) | Oryctolagus cuniculus (rabbit) | |
| 38 | LA (k) | ATP binding cassette subfamily E member 1 | polymer | 595 | 66986.8 | 1 | UniProt (G1SG72) Pfam (PF04068) Pfam (PF00037) Pfam (PF00005) | Oryctolagus cuniculus (rabbit) | |
| 39 | MA (l) | 60S ribosomal protein L41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) | Oryctolagus cuniculus (rabbit) | |
| 40 | NA (n) | 40S ribosomal protein S25 | polymer | 124 | 13645.0 | 1 | UniProt (G1TDB3) Pfam (PF03297) | Oryctolagus cuniculus (rabbit) | |
| 41 | AB, AC, AD, AE, AF... (2, 3, I, Z) | MAGNESIUM ION | non-polymer | 24.3 | 178 | Chemie (MG) |
Sequence modifications
I: 1 - 237 (UniProt: A0A5K1UJS7)
j: 5 - 115 (UniProt: G1SYS4)
k: 4 - 598 (UniProt: G1SG72)
| PDB | External Database | Details |
|---|---|---|
| Thr 130 | Pro 130 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ile 39 | Val 39 | conflict |
| Ile 76 | Val 76 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ile 538 | Val 538 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 40 |
| Total formula weight | 1330903.8 | |
| Non-Polymers* | Number of molecules | 178 |
| Total formula weight | 4326.3 | |
| All* | Total formula weight | 1335230.1 |
