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8OY2

Human cyclin-dependent kinase 2 in complex with inhibitor HB-29260

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cyclin-dependent kinase 2polymer30034104.61UniProt (P24941)
Pfam (PF00069)
Homo sapiens (human)Cell division protein kinase 2,p33 protein kinase
2B
(A)
(1S,2S,11aS)-1-methoxy-1,4,7,10-tetramethyl-2,9-bis(oxidanyl)-2,11a-dihydrobenzo[b][1,4]benzodioxepine-3,6-dionenon-polymer348.31Chemie (W5W)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.039Chemie (HOH)
Sequence modifications
A: 1 - 298 (UniProt: P24941)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34104.6
Non-Polymers*Number of molecules2
Total formula weight440.4
All*Total formula weight34545.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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