8OWV

H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (EEE)	Spike protein S1	polymer	209	23638.6	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	B (BBB)	F2	polymer	132	14962.6	1		Lama glama
3	C (FFF)	H6	polymer	133	14588.1	1		Lama glama
4	D (EEE)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	E, F, G (EEE, BBB)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
6	H, I, J (EEE, BBB, FFF)	water	water		18.0	216	Chemie (HOH)

Sequence modifications

EEE: 331 - 532 (UniProt: P0DTC2)

PDB	External Database	Details
Val 417	Lys 417	conflict
Lys 484	Glu 484	variant
Tyr 501	Asn 501	variant
Lys 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53189.3
Non-Polymers*	Number of molecules	4
	Total formula weight	497.5
All*	Total formula weight	53686.8

*Water molecules are not included.