8OW4
2.75 angstrom crystal structure of human NFAT1 with bound DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nuclear factor of activated T-cells, cytoplasmic 2 | polymer | 298 | 33870.5 | 2 | UniProt (Q13469) Pfam (PF00554) Pfam (PF16179) In PDB | Homo sapiens (human) | NF-ATc2,NFATc2,NFAT pre-existing subunit,NF-ATp,T-cell transcription factor NFAT1 |
2 | W, G | DNA (5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3') | polymer | 15 | 4657.1 | 2 | Homo sapiens | ||
3 | C, H | DNA (5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3') | polymer | 15 | 4519.0 | 2 | Homo sapiens | ||
4 | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A, B: 391 - 678 (UniProt: Q13469)
PDB | External Database | Details |
---|---|---|
Met 381 | - | initiating methionine |
Ala 382 | - | expression tag |
His 383 | - | expression tag |
His 384 | - | expression tag |
His 385 | - | expression tag |
His 386 | - | expression tag |
His 387 | - | expression tag |
His 388 | - | expression tag |
Val 389 | - | expression tag |
Gly 390 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 86093.1 | |
All* | Total formula weight | 86093.1 |