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8OW3

Crystal structure of wild-type c-MET bound by compound 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hepatocyte growth factor receptorpolymer30934842.31UniProt (P08581)
Pfam (PF07714)
Homo sapiens (human)HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2B
(A)
5-[3,5-bis(fluoranyl)phenyl]-1-[(1S)-1-phenylethyl]pyrimidine-2,4-dionenon-polymer328.31Chemie (W40)
3C
(A)
waterwater18.053Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34842.3
Non-Polymers*Number of molecules1
Total formula weight328.3
All*Total formula weight35170.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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