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8OUD

Structure of the human neutral amino acid transporter ASCT2 in complex with nanobody 469

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Neutral amino acid transporter B(0)polymer54156638.93UniProt (Q15758)
Pfam (PF00375)
Homo sapiens (human)ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5, Alanine Serine Cysteine Transporter 2
2D, E, F
(D, E, F)
Nanobody 469polymer12613792.43Lama glama
3G, H, I, L, M...
(A, B, C)
SODIUM IONnon-polymer23.09Chemie (NA)
4J, O, T
(A, B, C)
ALANINEnon-polymer89.13Chemie (ALA)
5K, P, U
(A, B, C)
CHOLESTEROL HEMISUCCINATEnon-polymer486.73Chemie (Y01)
6AA, V, W, X, Y...
(F, A, B, C, D...)
waterwater18.093Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight211293.9
Non-Polymers*Number of molecules15
Total formula weight1934.4
All*Total formula weight213228.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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