8OTV
Crystal structure of NUDT14 complexed with novel compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Uridine diphosphate glucose pyrophosphatase NUDT14 | polymer | 223 | 24228.3 | 2 | UniProt (O95848) In PDB | Homo sapiens (human) | UDPG pyrophosphatase,UGPPase,Nucleoside diphosphate-linked moiety X motif 14,Nudix motif 14 |
| 2 | A, B | 1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 400.5 | 2 | Chemie (W0O) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 222 (UniProt: O95848)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48456.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 903.4 | |
| All* | Total formula weight | 49360.0 |
