8OTS

OCT4 and MYC-MAX co-bound to a nucleosome

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125) In PDB	Homo sapiens (human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511) In PDB	Homo sapiens (human)
3	C, G	Histone H2A type 1-B/E	polymer	133	14447.8	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB	Homo sapiens (human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H	Histone H2B type 1-J	polymer	128	14088.3	2	UniProt (P06899) Pfam (PF00125) In PDB	Homo sapiens (human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I	DNA (127-MER)	polymer	127	39092.9	1		synthetic construct
6	J	DNA (127-MER)	polymer	127	39298.0	1		synthetic construct
7	K	Green fluorescent protein,POU domain, class 5, transcription factor 1	polymer	544	59814.4	1	UniProt (P42212) UniProt (Q01860) Pfam (PF01353) Pfam (PF00157) Pfam (PF00046) In PDB	Aequorea victoria (Water jellyfish)	Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3
8	M	Myc proto-oncogene protein	polymer	94	11501.2	1	UniProt (P01106) Pfam (PF02344) Pfam (PF00010) In PDB	Homo sapiens (human)	Class E basic helix-loop-helix protein 39,bHLHe39,Proto-oncogene c-Myc,Transcription factor p64
9	N	Protein max	polymer	82	9780.0	1	UniProt (P61244) Pfam (PF00010) In PDB	Homo sapiens (human)	Class D basic helix-loop-helix protein 4,bHLHd4,Myc-associated factor X
10	A, D, E, G, H	PENTANEDIAL	non-polymer		100.1	8	Chemie (PTD)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 0 - 129 (UniProt: P04908)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

D, H: 0 - 124 (UniProt: P06899)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

K: -246 - -10 (UniProt: P42212)

PDB	External Database	Details
Met -270	-	initiating methionine
Asp -269	-	expression tag
Trp -268	-	expression tag
Ser -267	-	expression tag
His -266	-	expression tag
Pro -265	-	expression tag
Gln -264	-	expression tag
Phe -263	-	expression tag
Glu -262	-	expression tag
Lys -261	-	expression tag
Ser -260	-	expression tag
Ala -259	-	expression tag
Val -258	-	expression tag
Asp -257	-	expression tag
Glu -256	-	expression tag
Asn -255	-	expression tag
Leu -254	-	expression tag
Tyr -253	-	expression tag
Phe -252	-	expression tag
Gln -251	-	expression tag
Gly -250	-	expression tag
Gly -249	-	expression tag
Met -248	-	expression tag
Val -247	-	expression tag
Leu -184	Phe 64	conflict
Thr -183	Ser 65	conflict
Lys -42	Ala 206	conflict
Leu -17	His 231	conflict
Glu -9	-	linker
Ala -8	-	linker
Ala -7	-	linker
Ala -6	-	linker
Lys -5	-	linker
Glu -4	-	linker
Ala -3	-	linker
Ala -2	-	linker
Ala -1	-	linker
Lys 0	-	linker

K: 1 - 273 (UniProt: Q01860)
M: 351 - 437 (UniProt: P01106)

PDB	External Database	Details
Met 344	-	initiating methionine
His 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag

N: 22 - 102 (UniProt: P61244)

PDB	External Database	Details
Met 21	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	13
	Total formula weight	271351.2
Non-Polymers*	Number of molecules	8
	Total formula weight	800.9
All*	Total formula weight	272152.1

*Water molecules are not included.