8OTN
structure of InhA from mycobacterium tuberculosis in complex with inhibitor 7-((1-(3-Hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methoxy)-4-methyl-2H-chromen-2-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 272 | 28837.1 | 4 | UniProt (P9WGR1) Pfam (PF13561) | Mycobacterium tuberculosis | ENR,Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | 4-methyl-7-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methoxy]chromen-2-one | non-polymer | 455.5 | 4 | Chemie (VZR) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 269 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 115348.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4475.5 | |
| All* | Total formula weight | 119823.8 |
