8OSL

Cryo-EM structure of CLOCK-BMAL1 bound to the native Por enhancer nucleosome (map 2, additional 3D classification and flexible refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125)	Homo sapiens (human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (human)
3	C, G (C, G)	Histone H2A type 1-B/E	polymer	133	14447.8	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H (D, H)	Histone H2B type 1-J	polymer	128	14088.3	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I (I)	DNA (147-MER)	polymer	147	45051.6	1		Homo sapiens
6	J (J)	DNA (147-MER)	polymer	147	45698.2	1		Homo sapiens
7	K, M (M, O)	Circadian locomoter output cycles protein kaput	polymer	375	43768.4	2	UniProt (O08785) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598)	Mus musculus (house mouse)	mCLOCK
8	L, N (N, P)	Basic helix-loop-helix ARNT-like protein 1	polymer	384	43821.2	2	UniProt (Q9WTL8) Pfam (PF00989) Pfam (PF14598) Pfam (PF00010)	Mus musculus (house mouse)	Arnt3,Aryl hydrocarbon receptor nuclear translocator-like protein 1,Brain and muscle ARNT-like 1

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

B, F: 0 - 102 (UniProt: P62805)

C, G: 0 - 129 (UniProt: P04908)

D, H: 0 - 124 (UniProt: P06899)

M, O: 26 - 395 (UniProt: O08785)

N, P: 69 - 447 (UniProt: Q9WTL8)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.