8ORW

Crystal structure of human STING in complex with the agonist MD1203

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Stimulator of interferon protein	polymer	204	23189.1	1	UniProt (A0A2R3XZB7) Pfam (PF15009) UniProt (by SIFTS) (Q86WV6)	Homo sapiens (human)
2	B (A)	9-[(1~{S},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one	non-polymer		661.4	1	Chemie (VZ6)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23189.1
Non-Polymers*	Number of molecules	1
	Total formula weight	661.4
All*	Total formula weight	23850.5

*Water molecules are not included.