8ORP

Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Alpha-amylase A	polymer	494	53797.3	2	UniProt (P08144) Pfam (PF00128) Pfam (PF02806) In PDB	Drosophila melanogaster (fruit fly)	1,4-alpha-D-glucan glucanohydrolase
2	C, E	4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose	branched		647.6	2	In PDB GlyTouCan (G45133CV)
3	D, F	4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose	branched		485.5	2	In PDB
4	B, A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	B, A	1,2-ETHANEDIOL	non-polymer		62.1	38	Chemie (EDO)
6	A, B	STRONTIUM ION	non-polymer		87.6	4	Chemie (SR)
7		water	water		18.0	875	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	107594.7
Branched	Number of molecules	4
	Total formula weight	2266.2
Non-Polymers*	Number of molecules	44
	Total formula weight	2780.0
All*	Total formula weight	112640.8

*Water molecules are not included.