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8ORJ

Cryo-EM structure of human tRNA ligase RTCB in complex with human PYROXD1.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-splicing ligase RtcB homologpolymer50855556.41UniProt (Q9Y3I0)
Pfam (PF01139)
Homo sapiens (human)3'-phosphate/5'-hydroxy nucleic acid ligase
2B
(B)
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1polymer50256016.91UniProt (Q8WU10)
Pfam (PF07992)
Pfam (PF18267)
Homo sapiens (human)
3C, D
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E
(B)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.41Chemie (NAD)
5F
(B)
DIHYDROFLAVINE-ADENINE DINUCLEOTIDEnon-polymer787.61Chemie (FDA)
Sequence modifications
A: 1 - 505 (UniProt: Q9Y3I0)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
B: 1 - 500 (UniProt: Q8WU10)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111573.3
Non-Polymers*Number of molecules4
Total formula weight1499.6
All*Total formula weight113072.9
*Water molecules are not included.

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PDB entries from 2026-01-28

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