8OQ8
CryoEM structure of human rho1 GABAA receptor in complex with pore blocker picrotoxin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | AA, F, G, IA, JA... (C, A, D, B, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 3 | BA, CA, DA, H, I... (C, A, D, B, E) | HEXANE | non-polymer | 86.2 | 15 | Chemie (HEX) | |||
| 4 | EA, GA, K, M, NA... (C, A, D, B, E) | DODECANE | non-polymer | 170.3 | 10 | Chemie (D12) | |||
| 5 | FA, HA, L, N, OA... (C, D, A, B, E) | DECANE | non-polymer | 142.3 | 10 | Chemie (D10) | |||
| 6 | O (A) | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione | non-polymer | 292.3 | 1 | Chemie (RI5) | |||
| 7 | AB, BB, CB, DB, ZA (B, C, D, E, A) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 46 |
| Total formula weight | 6923.2 | |
| All* | Total formula weight | 286674.3 |
