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8OO8

Three-Dimensional Structure of Human Carbonic Anhydrase II in Complex with a Covalent Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase 2polymer25929157.91UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
3-(cyclooctylamino)-4-ethylsulfonyl-2,5,6-tris(fluoranyl)benzenesulfonamidenon-polymer428.51Chemie (VV8)
4D
(A)
waterwater18.0338Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29157.9
Non-Polymers*Number of molecules2
Total formula weight493.9
All*Total formula weight29651.8
*Water molecules are not included.

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PDB entries from 2025-10-29

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