8OO5
Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | DDB1- and CUL4-associated factor 1 | polymer | 318 | 36062.6 | 1 | UniProt (Q9Y4B6) | Homo sapiens (human) | HIV-1 Vpr-binding protein,VprBP,Serine/threonine-protein kinase VPRBP,Vpr-interacting protein |
| 2 | B, C (P) | 1-[4-[4-(2-azanylethylamino)-2-[1-(4-chlorophenyl)cyclohexyl]quinazolin-7-yl]piperazin-1-yl]ethanone | non-polymer | 507.1 | 2 | Chemie (VUF) | |||
| 3 | D, E, F, G (P) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | H (P) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
P: 1079 - 1393 (UniProt: Q9Y4B6)
| PDB | External Database | Details |
|---|---|---|
| Gly 1076 | - | expression tag |
| Gly 1077 | - | expression tag |
| Gly 1078 | - | expression tag |
| Leu 1250 | Gln 1250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36062.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1262.4 | |
| All* | Total formula weight | 37325.0 |
