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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8OIT

39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1B1, B2, B3, B4, B5...39S ribosomal protein L12, mitochondrialpolymer19821378.26UniProt (P52815)
Pfam (PF16320)
Pfam (PF00542)
In PDB		Homo sapiens (human)L12mt,MRP-L12,5c5-2,Mitochondrial large ribosomal subunit protein bL12m
2B7E-site tRNApolymer3894.61Homo sapiens (human)
3B816S rRNApolymer1561500727.11GenBank (1563835895)Homo sapiens (human)
4B9CP Val-tRNA(Val)polymer7222989.81GenBank (NC_012920.1)Homo sapiens (human)
5BA39S ribosomal protein L22, mitochondrialpolymer20623683.71UniProt (Q9NWU5)
Pfam (PF00237)
In PDB		Homo sapiens (human)L22mt,MRP-L22,39S ribosomal protein L25,mitochondrial,L25mt,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m
6BB39S ribosomal protein L23, mitochondrialpolymer15317849.21UniProt (Q16540)
Pfam (PF00276)
In PDB		Homo sapiens (human)L23mt,MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like
7BC39S ribosomal protein L24, mitochondrialpolymer21624953.91UniProt (Q96A35)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Homo sapiens (human)MRP-L24,Mitochondrial large ribosomal subunit protein uL24m
8BD39S ribosomal protein L27, mitochondrialpolymer14816102.91UniProt (Q9P0M9)
Pfam (PF01016)
In PDB		Homo sapiens (human)MRP-L27,Mitochondrial large ribosomal subunit protein bL27m
9BE39S ribosomal protein L28, mitochondrialpolymer25630202.91UniProt (Q13084)
Pfam (PF00830)
In PDB		Homo sapiens (human)MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m
10BF39S ribosomal protein L47, mitochondrialpolymer25029508.51UniProt (Q9HD33)
Pfam (PF06984)
In PDB		Homo sapiens (human)MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1
11BG39S ribosomal protein L30, mitochondrialpolymer16118582.81UniProt (Q8TCC3)
Pfam (PF00327)
In PDB		Homo sapiens (human)MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m
12BH39S ribosomal protein L32, mitochondrialpolymer18821437.81UniProt (Q9BYC8)
Pfam (PF01783)
In PDB		Homo sapiens (human)MRP-L32,Mitochondrial large ribosomal subunit protein bL32m
13BI39S ribosomal protein L33, mitochondrialpolymer657635.21UniProt (O75394)
Pfam (PF00471)
In PDB		Homo sapiens (human)MRP-L33,Mitochondrial large ribosomal subunit protein bL33m
14BJ39S ribosomal protein L34, mitochondrialpolymer9210183.91UniProt (Q9BQ48)
Pfam (PF00468)
In PDB		Homo sapiens (human)MRP-L34,Mitochondrial large ribosomal subunit protein bL34m
15BK39S ribosomal protein L35, mitochondrialpolymer18821558.51UniProt (Q9NZE8)
Pfam (PF01632)
In PDB		Homo sapiens (human)MRP-L35,Mitochondrial large ribosomal subunit protein bL35m
16BL39S ribosomal protein L2, mitochondrialpolymer30533355.91UniProt (Q5T653)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Homo sapiens (human)MRP-L2,Mitochondrial large ribosomal subunit protein uL2m
17BM39S ribosomal protein L3, mitochondrialpolymer34838689.61UniProt (P09001)
Pfam (PF00297)
In PDB		Homo sapiens (human)MRP-L3,Mitochondrial large ribosomal subunit protein uL3m
18BN39S ribosomal protein L4, mitochondrialpolymer31134970.21UniProt (Q9BYD3)
Pfam (PF00573)
In PDB		Homo sapiens (human)MRP-L4,Mitochondrial large ribosomal subunit protein uL4m
19BO39S ribosomal protein L9, mitochondrialpolymer26730296.41UniProt (Q9BYD2)
Pfam (PF01281)
Pfam (PF22078)
In PDB		Homo sapiens (human)MRP-L9,Mitochondrial large ribosomal subunit protein bL9m
20BP39S ribosomal protein L10, mitochondrialpolymer26129322.51UniProt (Q7Z7H8)
Pfam (PF00466)
In PDB		Homo sapiens (human)MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m
21BQ39S ribosomal protein L11, mitochondrialpolymer19220716.21UniProt (Q9Y3B7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Homo sapiens (human)MRP-L11,Mitochondrial large ribosomal subunit protein uL11m
22BR39S ribosomal protein L13, mitochondrialpolymer17820765.01UniProt (Q9BYD1)
Pfam (PF00572)
In PDB		Homo sapiens (human)L13mt,MRP-L13,Mitochondrial large ribosomal subunit protein uL13m
23BS39S ribosomal protein L14, mitochondrialpolymer14515973.71UniProt (Q6P1L8)
Pfam (PF00238)
In PDB		Homo sapiens (human)MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m
24BT39S ribosomal protein L15, mitochondrialpolymer29633473.81UniProt (Q9P015)
Pfam (PF00828)
In PDB		Homo sapiens (human)MRP-L15,Mitochondrial large ribosomal subunit protein uL15m
25BU39S ribosomal protein L16, mitochondrialpolymer25128496.31UniProt (Q9NX20)
Pfam (PF00252)
In PDB		Homo sapiens (human)MRP-L16,Mitochondrial large ribosomal subunit protein uL16m
26BV39S ribosomal protein L17, mitochondrialpolymer17520083.31UniProt (Q9NRX2)
Pfam (PF01196)
In PDB		Homo sapiens (human)MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m
27BW39S ribosomal protein L18, mitochondrialpolymer18020607.61UniProt (Q9H0U6)
Pfam (PF00861)
In PDB		Homo sapiens (human)L18mt,MRP-L18,Mitochondrial large ribosomal subunit protein uL18m
28BX39S ribosomal protein L19, mitochondrialpolymer29233585.01UniProt (P49406)
Pfam (PF01245)
In PDB		Homo sapiens (human)MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m
29BY39S ribosomal protein L20, mitochondrialpolymer14917479.71UniProt (Q9BYC9)
Pfam (PF00453)
In PDB		Homo sapiens (human)MRP-L20,Mitochondrial large ribosomal subunit protein bL20m
30BZ39S ribosomal protein L21, mitochondrialpolymer20522847.71UniProt (Q7Z2W9)
Pfam (PF00829)
In PDB		Homo sapiens (human)MRP-L21,Mitochondrial large ribosomal subunit protein bL21m
31Ba39S ribosomal protein L52, mitochondrialpolymer12313682.71UniProt (Q86TS9)
Pfam (PF18699)
In PDB		Homo sapiens (human)L52mt,MRP-L52,Mitochondrial large ribosomal subunit protein mL52
32Bb39S ribosomal protein L53, mitochondrialpolymer11212167.91UniProt (Q96EL3)
Pfam (PF10780)
In PDB		Homo sapiens (human)L53mt,MRP-L53,Mitochondrial large ribosomal subunit protein mL53
33Bc39S ribosomal protein L54, mitochondrialpolymer13815844.21UniProt (Q6P161)
Pfam (PF08561)
In PDB		Homo sapiens (human)MRP-L54,Mitochondrial large ribosomal subunit protein mL54
34Bd39S ribosomal protein L55, mitochondrialpolymer12815160.41UniProt (Q7Z7F7)
Pfam (PF09776)
In PDB		Homo sapiens (human)MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55
35BeRibosomal protein 63, mitochondrialpolymer10212292.31UniProt (Q9BQC6)
Pfam (PF14978)
In PDB		Homo sapiens (human)hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57
36BfPeptidyl-tRNA hydrolase ICT1, mitochondrialpolymer20623674.21UniProt (Q14197)
Pfam (PF00472)
In PDB		Homo sapiens (human)39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62
37BgGrowth arrest and DNA damage-inducible proteins-interacting protein 1polymer22225426.91UniProt (Q8TAE8)
Pfam (PF10147)
In PDB		Homo sapiens (human)39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein
38Bh39S ribosomal protein S18a, mitochondrialpolymer19622224.11UniProt (Q9NVS2)
Pfam (PF01084)
In PDB		Homo sapiens (human)S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66
39Bi39S ribosomal protein S30, mitochondrialpolymer43950429.61UniProt (Q9NP92)
Pfam (PF07147)
In PDB		Homo sapiens (human)S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9
40Bj39S ribosomal protein L1, mitochondrialpolymer32536967.71UniProt (Q9BYD6)
Pfam (PF00687)
In PDB		Homo sapiens (human)L1mt,MRP-L1,Mitochondrial large ribosomal subunit protein uL1m
41Bl39S ribosomal protein L36, mitochondrialpolymer10311809.31UniProt (Q9P0J6)
Pfam (PF00444)
In PDB		Homo sapiens (human)MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m
42Bm39S ribosomal protein L37, mitochondrialpolymer42348183.31UniProt (Q9BZE1)
Pfam (PF07147)
In PDB		Homo sapiens (human)MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37
43Bn39S ribosomal protein L38, mitochondrialpolymer38044659.41UniProt (Q96DV4)
Pfam (PF01161)
In PDB		Homo sapiens (human)MRP-L38,Mitochondrial large ribosomal subunit protein mL38
44Bo39S ribosomal protein L39, mitochondrialpolymer33838764.81UniProt (Q9NYK5)
In PDB		Homo sapiens (human)MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39
45Bp39S ribosomal protein L40, mitochondrialpolymer20624534.41UniProt (Q9NQ50)
Pfam (PF09812)
In PDB		Homo sapiens (human)MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis
46Bq39S ribosomal protein L41, mitochondrialpolymer13715404.71UniProt (Q8IXM3)
Pfam (PF09809)
In PDB		Homo sapiens (human)MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41
47Br39S ribosomal protein L42, mitochondrialpolymer14216691.21UniProt (Q9Y6G3)
Pfam (PF10210)
In PDB		Homo sapiens (human)MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42
48BsLarge ribosomal subunit protein mL43polymer21523352.61UniProt (Q8N983)
Pfam (PF05047)
In PDB		Homo sapiens (human)39S ribosomal protein L43,mitochondrial,L43mt,MRP-L43,Mitochondrial ribosomal protein bMRP36a
49Bt39S ribosomal protein L44, mitochondrialpolymer33237583.31UniProt (Q9H9J2)
Pfam (PF22935)
Pfam (PF22892)
In PDB		Homo sapiens (human)MRP-L44,Mitochondrial large ribosomal subunit protein mL44
50Bu39S ribosomal protein L45, mitochondrialpolymer30635402.91UniProt (Q9BRJ2)
Pfam (PF04280)
In PDB		Homo sapiens (human)MRP-L45,Mitochondrial large ribosomal subunit protein mL45
51Bv39S ribosomal protein L46, mitochondrialpolymer27931748.11UniProt (Q9H2W6)
Pfam (PF11788)
In PDB		Homo sapiens (human)MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL
52Bw39S ribosomal protein L48, mitochondrialpolymer21223970.81UniProt (Q96GC5)
Pfam (PF00338)
In PDB		Homo sapiens (human)L48mt,MRP-L48,Mitochondrial large ribosomal subunit protein mL48
53Bx39S ribosomal protein L49, mitochondrialpolymer16619225.01UniProt (Q13405)
Pfam (PF05046)
In PDB		Homo sapiens (human)MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1
54By39S ribosomal protein L50, mitochondrialpolymer15818349.91UniProt (Q8N5N7)
Pfam (PF10501)
In PDB		Homo sapiens (human)MRP-L50,Mitochondrial large ribosomal subunit protein mL50
55Bz39S ribosomal protein L51, mitochondrialpolymer12815125.91UniProt (Q4U2R6)
Pfam (PF10244)
In PDB		Homo sapiens (human)MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64
56AGP-site Met-tRNA(Met)polymer7122692.51GenBank (NC_012920.1)Homo sapiens (human)
57AaPeptide chain release factor 1, mitochondrialpolymer48456258.41UniProt (O75570)
Pfam (PF03462)
Pfam (PF00472)
In PDB		Homo sapiens (human)MRF-1,MtRF-1
58B8, BT, Be, Bn, BLPOTASSIUM IONnon-polymer39.134Chemie (K)
59B8, BL, BN, BO, BR...MAGNESIUM IONnon-polymer24.3228Chemie (MG)
60B9VALINEnon-polymer117.11Chemie (VAL)
61Bl, BHZINC IONnon-polymer65.42Chemie (ZN)
62BhFE-S-O HYBRID CLUSTERnon-polymer335.51Chemie (FS2)
63AGMETHIONINEnon-polymer149.21Chemie (MET)
Sequence modifications
B9: 1 - 72 (GenBank: NC_012920.1)
PDBExternal DatabaseDetails
C 70G 1671conflict
A 72U 1673conflict
Bs: 2 - 215 (UniProt: Q8N983)
PDBExternal DatabaseDetails
Ace 2-acetylation
AG: 1 - 71 (GenBank: NC_012920.1)
PDBExternal DatabaseDetails
C 69-insertion
C 70-insertion
Aa: 1 - 445 (UniProt: O75570)
PDBExternal DatabaseDetails
Ala 311Gly 311engineered mutation
Ala 312Gly 312engineered mutation
Gly 446-expression tag
Gly 447-expression tag
Ser 448-expression tag
Gly 449-expression tag
Gly 450-expression tag
Ser 451-expression tag
Gly 452-expression tag
Gly 453-expression tag
Ser 454-expression tag
Gly 455-expression tag
Gly 456-expression tag
Ser 457-expression tag
Gly 458-expression tag
Gly 459-expression tag
Ser 460-expression tag
Gly 461-expression tag
Gly 462-expression tag
Asp 463-expression tag
Tyr 464-expression tag
Lys 465-expression tag
Asp 466-expression tag
His 467-expression tag
Asp 468-expression tag
Gly 469-expression tag
Asp 470-expression tag
Tyr 471-expression tag
Lys 472-expression tag
Asp 473-expression tag
His 474-expression tag
Asp 475-expression tag
Ile 476-expression tag
Asp 477-expression tag
Tyr 478-expression tag
Lys 479-expression tag
Asp 480-expression tag
Asp 481-expression tag
Asp 482-expression tag
Asp 483-expression tag
Lys 484-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains62
Total formula weight1986869.3
Non-Polymers*Number of molecules267
Total formula weight7603.6
All*Total formula weight1994472.9
*Water molecules are not included.

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PDB entries from 2024-08-14

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