8OIT
39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (B1, B2, B3, B4, B5...) | 39S ribosomal protein L12, mitochondrial | polymer | 198 | 21378.2 | 6 | UniProt (P52815) Pfam (PF16320) Pfam (PF00542) | Homo sapiens (human) | L12mt,MRP-L12,5c5-2,Mitochondrial large ribosomal subunit protein bL12m |
| 2 | G (B7) | E-site tRNA | polymer | 3 | 894.6 | 1 | Homo sapiens (human) | ||
| 3 | H (B8) | 16S rRNA | polymer | 1561 | 500727.1 | 1 | GenBank (1563835895) | Homo sapiens (human) | |
| 4 | I (B9) | CP Val-tRNA(Val) | polymer | 72 | 22989.8 | 1 | GenBank (NC_012920.1) | Homo sapiens (human) | |
| 5 | J (BA) | 39S ribosomal protein L22, mitochondrial | polymer | 206 | 23683.7 | 1 | UniProt (Q9NWU5) Pfam (PF00237) | Homo sapiens (human) | L22mt,MRP-L22,39S ribosomal protein L25,mitochondrial,L25mt,MRP-L25,Mitochondrial large ribosomal subunit protein uL22m |
| 6 | K (BB) | 39S ribosomal protein L23, mitochondrial | polymer | 153 | 17849.2 | 1 | UniProt (Q16540) Pfam (PF00276) | Homo sapiens (human) | L23mt,MRP-L23,L23 mitochondrial-related protein,Mitochondrial large ribosomal subunit protein uL23m,Ribosomal protein L23-like |
| 7 | L (BC) | 39S ribosomal protein L24, mitochondrial | polymer | 216 | 24953.9 | 1 | UniProt (Q96A35) Pfam (PF00467) Pfam (PF17136) | Homo sapiens (human) | MRP-L24,Mitochondrial large ribosomal subunit protein uL24m |
| 8 | M (BD) | 39S ribosomal protein L27, mitochondrial | polymer | 148 | 16102.9 | 1 | UniProt (Q9P0M9) Pfam (PF01016) | Homo sapiens (human) | MRP-L27,Mitochondrial large ribosomal subunit protein bL27m |
| 9 | N (BE) | 39S ribosomal protein L28, mitochondrial | polymer | 256 | 30202.9 | 1 | UniProt (Q13084) Pfam (PF00830) | Homo sapiens (human) | MRP-L28,Melanoma antigen p15,Melanoma-associated antigen recognized by T-lymphocytes,Mitochondrial large ribosomal subunit protein bL28m |
| 10 | O (BF) | 39S ribosomal protein L47, mitochondrial | polymer | 250 | 29508.5 | 1 | UniProt (Q9HD33) Pfam (PF06984) | Homo sapiens (human) | MRP-L47,Mitochondrial large ribosomal subunit protein uL29m,Nasopharyngeal carcinoma metastasis-related protein 1 |
| 11 | P (BG) | 39S ribosomal protein L30, mitochondrial | polymer | 161 | 18582.8 | 1 | UniProt (Q8TCC3) Pfam (PF00327) | Homo sapiens (human) | MRP-L30,39S ribosomal protein L28,mitochondrial,MRP-L28,Mitochondrial large ribosomal subunit protein uL30m |
| 12 | Q (BH) | 39S ribosomal protein L32, mitochondrial | polymer | 188 | 21437.8 | 1 | UniProt (Q9BYC8) Pfam (PF01783) | Homo sapiens (human) | MRP-L32,Mitochondrial large ribosomal subunit protein bL32m |
| 13 | R (BI) | 39S ribosomal protein L33, mitochondrial | polymer | 65 | 7635.2 | 1 | UniProt (O75394) Pfam (PF00471) | Homo sapiens (human) | MRP-L33,Mitochondrial large ribosomal subunit protein bL33m |
| 14 | S (BJ) | 39S ribosomal protein L34, mitochondrial | polymer | 92 | 10183.9 | 1 | UniProt (Q9BQ48) Pfam (PF00468) | Homo sapiens (human) | MRP-L34,Mitochondrial large ribosomal subunit protein bL34m |
| 15 | T (BK) | 39S ribosomal protein L35, mitochondrial | polymer | 188 | 21558.5 | 1 | UniProt (Q9NZE8) Pfam (PF01632) | Homo sapiens (human) | MRP-L35,Mitochondrial large ribosomal subunit protein bL35m |
| 16 | U (BL) | 39S ribosomal protein L2, mitochondrial | polymer | 305 | 33355.9 | 1 | UniProt (Q5T653) Pfam (PF00181) Pfam (PF03947) | Homo sapiens (human) | MRP-L2,Mitochondrial large ribosomal subunit protein uL2m |
| 17 | V (BM) | 39S ribosomal protein L3, mitochondrial | polymer | 348 | 38689.6 | 1 | UniProt (P09001) Pfam (PF00297) | Homo sapiens (human) | MRP-L3,Mitochondrial large ribosomal subunit protein uL3m |
| 18 | W (BN) | 39S ribosomal protein L4, mitochondrial | polymer | 311 | 34970.2 | 1 | UniProt (Q9BYD3) Pfam (PF00573) | Homo sapiens (human) | MRP-L4,Mitochondrial large ribosomal subunit protein uL4m |
| 19 | X (BO) | 39S ribosomal protein L9, mitochondrial | polymer | 267 | 30296.4 | 1 | UniProt (Q9BYD2) Pfam (PF01281) Pfam (PF22078) | Homo sapiens (human) | MRP-L9,Mitochondrial large ribosomal subunit protein bL9m |
| 20 | Y (BP) | 39S ribosomal protein L10, mitochondrial | polymer | 261 | 29322.5 | 1 | UniProt (Q7Z7H8) Pfam (PF00466) | Homo sapiens (human) | MRP-L10,39S ribosomal protein L8,mitochondrial,MRP-L8,Mitochondrial large ribosomal subunit protein uL10m |
| 21 | Z (BQ) | 39S ribosomal protein L11, mitochondrial | polymer | 192 | 20716.2 | 1 | UniProt (Q9Y3B7) Pfam (PF03946) Pfam (PF00298) | Homo sapiens (human) | MRP-L11,Mitochondrial large ribosomal subunit protein uL11m |
| 22 | AA (BR) | 39S ribosomal protein L13, mitochondrial | polymer | 178 | 20765.0 | 1 | UniProt (Q9BYD1) Pfam (PF00572) | Homo sapiens (human) | L13mt,MRP-L13,Mitochondrial large ribosomal subunit protein uL13m |
| 23 | BA (BS) | 39S ribosomal protein L14, mitochondrial | polymer | 145 | 15973.7 | 1 | UniProt (Q6P1L8) Pfam (PF00238) | Homo sapiens (human) | MRP-L14,39S ribosomal protein L32,mitochondrial,MRP-L32,Mitochondrial large ribosomal subunit protein uL14m |
| 24 | CA (BT) | 39S ribosomal protein L15, mitochondrial | polymer | 296 | 33473.8 | 1 | UniProt (Q9P015) Pfam (PF00828) | Homo sapiens (human) | MRP-L15,Mitochondrial large ribosomal subunit protein uL15m |
| 25 | DA (BU) | 39S ribosomal protein L16, mitochondrial | polymer | 251 | 28496.3 | 1 | UniProt (Q9NX20) Pfam (PF00252) | Homo sapiens (human) | MRP-L16,Mitochondrial large ribosomal subunit protein uL16m |
| 26 | EA (BV) | 39S ribosomal protein L17, mitochondrial | polymer | 175 | 20083.3 | 1 | UniProt (Q9NRX2) Pfam (PF01196) | Homo sapiens (human) | MRP-L17,LYST-interacting protein 2,Mitochondrial large ribosomal subunit protein bL17m |
| 27 | FA (BW) | 39S ribosomal protein L18, mitochondrial | polymer | 180 | 20607.6 | 1 | UniProt (Q9H0U6) Pfam (PF00861) | Homo sapiens (human) | L18mt,MRP-L18,Mitochondrial large ribosomal subunit protein uL18m |
| 28 | GA (BX) | 39S ribosomal protein L19, mitochondrial | polymer | 292 | 33585.0 | 1 | UniProt (P49406) Pfam (PF01245) | Homo sapiens (human) | MRP-L19,39S ribosomal protein L15,mitochondrial,MRP-L15,Mitochondrial large ribosomal subunit protein bL19m |
| 29 | HA (BY) | 39S ribosomal protein L20, mitochondrial | polymer | 149 | 17479.7 | 1 | UniProt (Q9BYC9) Pfam (PF00453) | Homo sapiens (human) | MRP-L20,Mitochondrial large ribosomal subunit protein bL20m |
| 30 | IA (BZ) | 39S ribosomal protein L21, mitochondrial | polymer | 205 | 22847.7 | 1 | UniProt (Q7Z2W9) Pfam (PF00829) | Homo sapiens (human) | MRP-L21,Mitochondrial large ribosomal subunit protein bL21m |
| 31 | JA (Ba) | 39S ribosomal protein L52, mitochondrial | polymer | 123 | 13682.7 | 1 | UniProt (Q86TS9) Pfam (PF18699) | Homo sapiens (human) | L52mt,MRP-L52,Mitochondrial large ribosomal subunit protein mL52 |
| 32 | KA (Bb) | 39S ribosomal protein L53, mitochondrial | polymer | 112 | 12167.9 | 1 | UniProt (Q96EL3) Pfam (PF10780) | Homo sapiens (human) | L53mt,MRP-L53,Mitochondrial large ribosomal subunit protein mL53 |
| 33 | LA (Bc) | 39S ribosomal protein L54, mitochondrial | polymer | 138 | 15844.2 | 1 | UniProt (Q6P161) Pfam (PF08561) | Homo sapiens (human) | MRP-L54,Mitochondrial large ribosomal subunit protein mL54 |
| 34 | MA (Bd) | 39S ribosomal protein L55, mitochondrial | polymer | 128 | 15160.4 | 1 | UniProt (Q7Z7F7) Pfam (PF09776) | Homo sapiens (human) | MRP-L55,Mitochondrial large ribosomal subunit protein bL31m,Mitochondrial large ribosomal subunit protein mL55 |
| 35 | NA (Be) | Ribosomal protein 63, mitochondrial | polymer | 102 | 12292.3 | 1 | UniProt (Q9BQC6) Pfam (PF14978) | Homo sapiens (human) | hMRP63,Mitochondrial large ribosomal subunit protein mL63,Mitochondrial ribosomal protein 63,Mitochondrial ribosomal protein L57 |
| 36 | OA (Bf) | Peptidyl-tRNA hydrolase ICT1, mitochondrial | polymer | 206 | 23674.2 | 1 | UniProt (Q14197) Pfam (PF00472) | Homo sapiens (human) | 39S ribosomal protein L58,mitochondrial,MRP-L58,Digestion substraction 1,DS-1,Immature colon carcinoma transcript 1 protein,Mitochondrial large ribosomal subunit protein mL62 |
| 37 | PA (Bg) | Growth arrest and DNA damage-inducible proteins-interacting protein 1 | polymer | 222 | 25426.9 | 1 | UniProt (Q8TAE8) Pfam (PF10147) | Homo sapiens (human) | 39S ribosomal protein L59,mitochondrial,MRP-L59,CKII beta-associating protein,CR6-interacting factor 1,CRIF1,Mitochondrial large ribosomal subunit protein mL64,Papillomavirus L2-interacting nuclear protein 1,PLINP-1,p53-responsive gene 6 protein |
| 38 | QA (Bh) | 39S ribosomal protein S18a, mitochondrial | polymer | 196 | 22224.1 | 1 | UniProt (Q9NVS2) Pfam (PF01084) | Homo sapiens (human) | S18mt-a,39S ribosomal protein S18-3,mitochondrial,MRP-S18-3,Mitochondrial large ribosomal subunit protein bS18a,Mitochondrial large ribosomal subunit protein mL66 |
| 39 | RA (Bi) | 39S ribosomal protein S30, mitochondrial | polymer | 439 | 50429.6 | 1 | UniProt (Q9NP92) Pfam (PF07147) | Homo sapiens (human) | S30mt,Mitochondrial large ribosomal subunit protein mL65,Mitochondrial large ribosomal subunit protein mS30,Programmed cell death protein 9 |
| 40 | SA (Bj) | 39S ribosomal protein L1, mitochondrial | polymer | 325 | 36967.7 | 1 | UniProt (Q9BYD6) Pfam (PF00687) | Homo sapiens (human) | L1mt,MRP-L1,Mitochondrial large ribosomal subunit protein uL1m |
| 41 | TA (Bl) | 39S ribosomal protein L36, mitochondrial | polymer | 103 | 11809.3 | 1 | UniProt (Q9P0J6) Pfam (PF00444) | Homo sapiens (human) | MRP-L36,BRCA1-interacting protein 1,Mitochondrial large ribosomal subunit protein bL36m |
| 42 | UA (Bm) | 39S ribosomal protein L37, mitochondrial | polymer | 423 | 48183.3 | 1 | UniProt (Q9BZE1) Pfam (PF07147) | Homo sapiens (human) | MRP-L37,39S ribosomal protein L2,mitochondrial,MRP-L2,Mitochondrial large ribosomal subunit protein mL37 |
| 43 | VA (Bn) | 39S ribosomal protein L38, mitochondrial | polymer | 380 | 44659.4 | 1 | UniProt (Q96DV4) Pfam (PF01161) | Homo sapiens (human) | MRP-L38,Mitochondrial large ribosomal subunit protein mL38 |
| 44 | WA (Bo) | 39S ribosomal protein L39, mitochondrial | polymer | 338 | 38764.8 | 1 | UniProt (Q9NYK5) | Homo sapiens (human) | MRP-L39,39S ribosomal protein L5,mitochondrial,MRP-L5,Mitochondrial large ribosomal subunit protein mL39 |
| 45 | XA (Bp) | 39S ribosomal protein L40, mitochondrial | polymer | 206 | 24534.4 | 1 | UniProt (Q9NQ50) Pfam (PF09812) | Homo sapiens (human) | MRP-L40,Mitochondrial large ribosomal subunit protein mL40,Nuclear localization signal-containing protein deleted in velocardiofacial syndrome,Up-regulated in metastasis |
| 46 | YA (Bq) | 39S ribosomal protein L41, mitochondrial | polymer | 137 | 15404.7 | 1 | UniProt (Q8IXM3) Pfam (PF09809) | Homo sapiens (human) | MRP-L41,39S ribosomal protein L27 homolog,Bcl-2-interacting mitochondrial ribosomal protein L41,Cell proliferation-inducing gene 3 protein,MRP-L27 homolog,Mitochondrial large ribosomal subunit protein mL41 |
| 47 | ZA (Br) | 39S ribosomal protein L42, mitochondrial | polymer | 142 | 16691.2 | 1 | UniProt (Q9Y6G3) Pfam (PF10210) | Homo sapiens (human) | MRP-L42,39S ribosomal protein L31,mitochondrial,MRP-L31,Mitochondrial large ribosomal subunit protein mL42 |
| 48 | AB (Bs) | Large ribosomal subunit protein mL43 | polymer | 215 | 23352.6 | 1 | UniProt (Q8N983) Pfam (PF05047) | Homo sapiens (human) | 39S ribosomal protein L43,mitochondrial,L43mt,MRP-L43,Mitochondrial ribosomal protein bMRP36a |
| 49 | BB (Bt) | 39S ribosomal protein L44, mitochondrial | polymer | 332 | 37583.3 | 1 | UniProt (Q9H9J2) Pfam (PF22935) Pfam (PF22892) | Homo sapiens (human) | MRP-L44,Mitochondrial large ribosomal subunit protein mL44 |
| 50 | CB (Bu) | 39S ribosomal protein L45, mitochondrial | polymer | 306 | 35402.9 | 1 | UniProt (Q9BRJ2) Pfam (PF04280) | Homo sapiens (human) | MRP-L45,Mitochondrial large ribosomal subunit protein mL45 |
| 51 | DB (Bv) | 39S ribosomal protein L46, mitochondrial | polymer | 279 | 31748.1 | 1 | UniProt (Q9H2W6) Pfam (PF11788) | Homo sapiens (human) | MRP-L46,Mitochondrial large ribosomal subunit protein mL46,P2ECSL |
| 52 | EB (Bw) | 39S ribosomal protein L48, mitochondrial | polymer | 212 | 23970.8 | 1 | UniProt (Q96GC5) Pfam (PF00338) | Homo sapiens (human) | L48mt,MRP-L48,Mitochondrial large ribosomal subunit protein mL48 |
| 53 | FB (Bx) | 39S ribosomal protein L49, mitochondrial | polymer | 166 | 19225.0 | 1 | UniProt (Q13405) Pfam (PF05046) | Homo sapiens (human) | MRP-L49,Mitochondrial large ribosomal subunit protein mL49,Neighbor of FAU,NOF,Protein NOF1 |
| 54 | GB (By) | 39S ribosomal protein L50, mitochondrial | polymer | 158 | 18349.9 | 1 | UniProt (Q8N5N7) Pfam (PF10501) | Homo sapiens (human) | MRP-L50,Mitochondrial large ribosomal subunit protein mL50 |
| 55 | HB (Bz) | 39S ribosomal protein L51, mitochondrial | polymer | 128 | 15125.9 | 1 | UniProt (Q4U2R6) Pfam (PF10244) | Homo sapiens (human) | MRP-L51,Mitochondrial large ribosomal subunit protein mL51,bMRP-64,bMRP64 |
| 56 | IB (AG) | P-site Met-tRNA(Met) | polymer | 71 | 22692.5 | 1 | GenBank (NC_012920.1) | Homo sapiens (human) | |
| 57 | JB (Aa) | Peptide chain release factor 1, mitochondrial | polymer | 484 | 56258.4 | 1 | UniProt (O75570) Pfam (PF03462) Pfam (PF00472) | Homo sapiens (human) | MRF-1,MtRF-1 |
| 58 | AC, BC, CC, DC, EC... (B8, BT, Be, Bn, BL) | POTASSIUM ION | non-polymer | 39.1 | 34 | Chemie (K) | |||
| 59 | AD, AE, AF, AG, AH... (B8, BL, BN, BO, BR...) | MAGNESIUM ION | non-polymer | 24.3 | 228 | Chemie (MG) | |||
| 60 | WK (B9) | VALINE | non-polymer | 117.1 | 1 | Chemie (VAL) | |||
| 61 | LL, YK (Bl, BH) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 62 | KL (Bh) | FE-S-O HYBRID CLUSTER | non-polymer | 335.5 | 1 | Chemie (FS2) | |||
| 63 | OL (AG) | METHIONINE | non-polymer | 149.2 | 1 | Chemie (MET) |
Sequence modifications
B9: 1 - 72 (GenBank: NC_012920.1)
Bs: 2 - 215 (UniProt: Q8N983)
AG: 1 - 71 (GenBank: NC_012920.1)
Aa: 1 - 445 (UniProt: O75570)
| PDB | External Database | Details |
|---|---|---|
| C 70 | G 1671 | conflict |
| A 72 | U 1673 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ace 2 | - | acetylation |
| PDB | External Database | Details |
|---|---|---|
| C 69 | - | insertion |
| C 70 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ala 311 | Gly 311 | engineered mutation |
| Ala 312 | Gly 312 | engineered mutation |
| Gly 446 | - | expression tag |
| Gly 447 | - | expression tag |
| Ser 448 | - | expression tag |
| Gly 449 | - | expression tag |
| Gly 450 | - | expression tag |
| Ser 451 | - | expression tag |
| Gly 452 | - | expression tag |
| Gly 453 | - | expression tag |
| Ser 454 | - | expression tag |
| Gly 455 | - | expression tag |
| Gly 456 | - | expression tag |
| Ser 457 | - | expression tag |
| Gly 458 | - | expression tag |
| Gly 459 | - | expression tag |
| Ser 460 | - | expression tag |
| Gly 461 | - | expression tag |
| Gly 462 | - | expression tag |
| Asp 463 | - | expression tag |
| Tyr 464 | - | expression tag |
| Lys 465 | - | expression tag |
| Asp 466 | - | expression tag |
| His 467 | - | expression tag |
| Asp 468 | - | expression tag |
| Gly 469 | - | expression tag |
| Asp 470 | - | expression tag |
| Tyr 471 | - | expression tag |
| Lys 472 | - | expression tag |
| Asp 473 | - | expression tag |
| His 474 | - | expression tag |
| Asp 475 | - | expression tag |
| Ile 476 | - | expression tag |
| Asp 477 | - | expression tag |
| Tyr 478 | - | expression tag |
| Lys 479 | - | expression tag |
| Asp 480 | - | expression tag |
| Asp 481 | - | expression tag |
| Asp 482 | - | expression tag |
| Asp 483 | - | expression tag |
| Lys 484 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 62 |
| Total formula weight | 1986869.3 | |
| Non-Polymers* | Number of molecules | 267 |
| Total formula weight | 7603.6 | |
| All* | Total formula weight | 1994472.9 |
