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8OI1

Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep4)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, O
(A, O)
Proteasome subunit alpha type-2polymer25027191.82UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
2B, P
(B, P)
Proteasome subunit alpha type-3polymer25828748.22UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
3C, Q
(C, Q)
Proteasome subunit alpha type-4polymer25428478.12UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
4D, R
(D, R)
Proteasome subunit alpha type-5polymer26028649.12UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
5E, S
(E, S)
Proteasome subunit alpha type-6polymer23425634.02UniProt (P40302)
Pfam (PF00227)
Pfam (PF10584)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
6F, T
(F, T)
Probable proteasome subunit alpha type-7polymer28831575.12UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
7G, U
(G, U)
Proteasome subunit alpha type-1polymer25228033.82UniProt (P21243)
Pfam (PF10584)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
8H, V
(H, V)
Proteasome subunit beta type-2polymer23225114.52UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1
9I, W
(I, W)
Proteasome subunit beta type-3polymer20522627.82UniProt (P25451)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3
10J, X
(J, X)
Proteasome subunit beta type-4polymer19822545.72UniProt (P22141)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11
11K, Y
(K, Y)
Proteasome subunit beta type-5polymer21223325.22UniProt (P30656)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2
12L, Z
(L, Z)
Proteasome subunit beta type-6polymer22224883.92UniProt (P23724)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Multicatalytic endopeptidase complex subunit C5,Proteasome component C5
13AA, M
(M, a)
Proteasome subunit beta type-7polymer24627200.92UniProt (P30657)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
14BA, N
(N, b)
Proteasome subunit beta type-1polymer19621517.22UniProt (P38624)
Pfam (PF00227)
Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
15CA, EA, FA, GA, IA...
(G, I, J, K, N...)
MAGNESIUM IONnon-polymer24.311Chemie (MG)
16DA, HA, OA, QA
(H, K, V, Y)
~{N}-[(2~{S},3~{R})-1-[[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]amino]-3-oxidanyl-1-oxidanylidene-butan-2-yl]-7-[4-[2-(4-methylphenyl)hydrazinyl]phenyl]heptanamidenon-polymer652.84Chemie (VOX)
17MA, TA
(N, b)
CHLORIDE IONnon-polymer35.52Chemie (CL)
18NA, UA
(N, b)
SULFATE IONnon-polymer96.12Chemie (SO4)
19AB, BB, CB, DB, EB...
(F, G, H, I, J...)
waterwater18.0213Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains28
Total formula weight731050.8
Non-Polymers*Number of molecules19
Total formula weight3141.7
All*Total formula weight734192.5
*Water molecules are not included.

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PDB entries from 2024-11-27

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