8OG9
Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DDB1- and CUL4-associated factor 1 | polymer | 367 | 41764.8 | 1 | UniProt (Q9Y4B6) In PDB | Homo sapiens (human) | HIV-1 Vpr-binding protein,VprBP,Serine/threonine-protein kinase VPRBP,Vpr-interacting protein |
2 | A | 5-[1-(4-chlorophenyl)cyclopropyl]imidazo[2,1-a]isoquinoline | non-polymer | 318.8 | 2 | Chemie (VM3) | |||
3 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 1039 - 1401 (UniProt: Q9Y4B6)
PDB | External Database | Details |
---|---|---|
Gly 1035 | - | expression tag |
Gly 1036 | - | expression tag |
Gly 1037 | - | expression tag |
Arg 1038 | - | expression tag |
Leu 1250 | Gln 1250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41764.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 637.6 | |
All* | Total formula weight | 42402.4 |