8OFM

Structure of the ALDEHYDE DEHYDROGENASE 5F1 (ALDH5F1) from the moss Physcomitrium patens in complex with NAD in an extended conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Succinate-semialdehyde dehydrogenase	polymer	512	54688.7	2	UniProt (A0A2K1ICJ7) Pfam (PF00171) In PDB	Physcomitrium patens
2	A	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
3	B, A	GLYCEROL	non-polymer		92.1	13	Chemie (GOL)
4	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
5	B, A	SULFATE ION	non-polymer		96.1	15	Chemie (SO4)
6		water	water		18.0	699	Chemie (HOH)

Sequence modifications

A, B: 1 - 492 (UniProt: A0A2K1ICJ7)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	109377.5
Non-Polymers*	Number of molecules	35
	Total formula weight	4275.4
All*	Total formula weight	113652.8

*Water molecules are not included.