8KHM

Crystal structure of human methionine aminopeptidase 12 (MAP12) in the unbound form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Methionine aminopeptidase 1D, mitochondrial	polymer	313	34384.6	1	UniProt (Q6UB28) Pfam (PF00557)	Homo sapiens (human)	MAP 1D,MetAP 1D,Methionyl aminopeptidase type 1D,mitochondrial,Peptidase M 1D
2	B (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E (A)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

A: 44 - 335 (UniProt: Q6UB28)

PDB	External Database	Details
Met 23	-	initiating methionine
Gly 24	-	expression tag
Ser 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Ser 33	-	expression tag
Ser 34	-	expression tag
Gly 35	-	expression tag
Leu 36	-	expression tag
Val 37	-	expression tag
Pro 38	-	expression tag
Arg 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag
His 42	-	expression tag
Met 43	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34384.6
Non-Polymers*	Number of molecules	3
	Total formula weight	334.4
All*	Total formula weight	34719.0

*Water molecules are not included.