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8KF1

The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(G, F, H, A, I...)
P3(40)polymer77087046.212UniProt (P05067)
Pfam (PF02177)
Pfam (PF12924)
Pfam (PF00014)
Pfam (PF12925)
Pfam (PF03494)
Pfam (PF10515)
Homo sapiens (human)
2M, N
(F, J)
4-[2-[6-[2-[2-(2-fluoranylethoxy)ethoxy]ethoxy]pyridin-3-yl]ethyl]-~{N}-methyl-anilinenon-polymer362.42Chemie (VW6)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight1044554.6
Non-Polymers*Number of molecules2
Total formula weight724.9
All*Total formula weight1045279.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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