8KDB

Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in dimeric form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, G (A, G)	RNA-directed RNA polymerase L	polymer	2266	260103.7	2	UniProt (O89238) Pfam (PF00946) Pfam (PF14318)	Human respirovirus 3
2	B, C, D, E, F (B, C, D, E, F)	Phosphoprotein	polymer	609	68471.3	5	UniProt (O89234) Pfam (PF01806)	Human respirovirus 3
3	H (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	I, J (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, G: -24 - 2233 (UniProt: O89238)

PDB	External Database	Details
Asp 2234	-	expression tag
Tyr 2235	-	expression tag
Lys 2236	-	expression tag
Asp 2237	-	expression tag
Asp 2238	-	expression tag
Asp 2239	-	expression tag
Asp 2240	-	expression tag
Lys 2241	-	expression tag

B, C, D, E, F: 1 - 603 (UniProt: O89234)

PDB	External Database	Details
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	862564.0
Non-Polymers*	Number of molecules	3
	Total formula weight	155.1
All*	Total formula weight	862719.1

*Water molecules are not included.