8KD5
Rpd3S in complex with nucleosome with H3K36MLA modification and 187bp DNA, class2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (D, F) | Chromatin modification-related protein EAF3 | polymer | 401 | 45266.4 | 2 | UniProt (Q12432) Pfam (PF11717) Pfam (PF22732) Pfam (PF05712) | Saccharomyces cerevisiae (baker's yeast) | ESA1-associated factor 3 |
| 2 | C, G (O, S) | Histone H3 | polymer | 135 | 15313.9 | 2 | UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) | Xenopus laevis (African clawed frog) | |
| 3 | D, H (P, T) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 4 | E, I (Q, U) | Histone H2A | polymer | 129 | 13978.2 | 2 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) | Xenopus laevis (African clawed frog) | |
| 5 | F, J (R, V) | Histone H2B 1.1 | polymer | 122 | 13524.8 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 6 | K (X) | 187bp DNA | polymer | 187 | 58077.9 | 1 | synthetic construct | ||
| 7 | L (Y) | 187bp DNA | polymer | 187 | 57397.5 | 1 | synthetic construct | ||
| 8 | M (A) | Histone deacetylase RPD3 | polymer | 433 | 48962.0 | 1 | UniProt (P32561) Pfam (PF00850) | Saccharomyces cerevisiae (baker's yeast) | |
| 9 | N (B) | Transcriptional regulatory protein SIN3 | polymer | 1544 | 176152.4 | 1 | UniProt (P22579) Pfam (PF02671) Pfam (PF08295) Pfam (PF16879) | Saccharomyces cerevisiae (baker's yeast) | |
| 10 | O, P (E, G) | Transcriptional regulatory protein RCO1 | polymer | 684 | 78951.3 | 2 | UniProt (Q04779) Pfam (PF00628) | Saccharomyces cerevisiae (baker's yeast) | |
| 11 | Q (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
O, S: 1 - 135 (UniProt: A0A310TTQ1)
R, V: 1 - 122 (UniProt: P02281)
B: 2 - 1536 (UniProt: P22579)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Cys 111 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 697185.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 697251.0 |
