8KCW
Cryo-EM structure of human SIDT1 bound to cholesterol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | SID1 transmembrane family member 1 | polymer | 850 | 96877.3 | 2 | UniProt (Q9NXL6) Pfam (PF13965) In PDB | Homo sapiens (human) | |
2 | G, H, M, N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 4 | In PDB GlyTouCan (G15407YE) | |||
3 | I, J, O, P | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
4 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A, C | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) |
Sequence modifications
A, C: 1 - 827 (UniProt: Q9NXL6)
PDB | External Database | Details |
---|---|---|
Glu 828 | - | expression tag |
Asn 829 | - | expression tag |
Leu 830 | - | expression tag |
Tyr 831 | - | expression tag |
Phe 832 | - | expression tag |
Gln 833 | - | expression tag |
Gly 834 | - | expression tag |
Asp 835 | - | expression tag |
Tyr 836 | - | expression tag |
Lys 837 | - | expression tag |
Asp 838 | - | expression tag |
Asp 839 | - | expression tag |
Asp 840 | - | expression tag |
Asp 841 | - | expression tag |
Lys 842 | - | expression tag |
His 843 | - | expression tag |
His 844 | - | expression tag |
His 845 | - | expression tag |
His 846 | - | expression tag |
His 847 | - | expression tag |
His 848 | - | expression tag |
His 849 | - | expression tag |
His 850 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 193754.6 | |
Branched | Number of molecules | 8 |
Total formula weight | 4043.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1677.4 | |
All* | Total formula weight | 199475.8 |