8KA0
Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-bound calmodulin and a nicotinamide adenine dinucleotide (NAD+)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | RDTND-RID CBD | polymer | 416 | 47092.2 | 4 | UniProt (A0A2S3R7M0) | Vibrio vulnificus | MARTX |
| 2 | B, D, F, H (B, D, F, H) | Calmodulin-2 | polymer | 151 | 16979.7 | 4 | UniProt (P0DP24) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | I, L, Q, V (A, C, E, G) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | J, K, N, O, S... (B, D, F, H) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 5 | M, P, R, U (C, D, F) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 616 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1959 - 2374 (UniProt: A0A2S3R7M0)
B, D, F, H: 1 - 149 (UniProt: P0DP24)
| PDB | External Database | Details |
|---|---|---|
| Gln 2186 | Glu 2186 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ala 0 | - | cloning artifact |
| Gln 124 | Glu 124 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 256287.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3342.7 | |
| All* | Total formula weight | 259630.1 |
