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8K8S

F8-A22-E4 complex of MPXV in complex with DNA and Ara-CTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase F8polymer1006117045.11Pfam (PF08452)
Pfam (PF03104)
Pfam (PF08408)
Pfam (PF00136)
UniProt (by SIFTS) (A0A7H0DN44)
Monkeypox virus
2B
(B)
Uracil-DNA glycosylase E4polymer21825107.71UniProt (by SIFTS) (M1LL92)Monkeypox virus
3C
(C)
DNA polymerase processivity factor component A20polymer42649203.91UniProt (Q5IXP2)
Pfam (PF05941)
UniProt (by SIFTS) (A0A7H0DNC0)
Monkeypox virus
4D
(E)
DNA (5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*C)-3')polymer123518.31DNA molecule
5E
(F)
DNA (5'-D(P*TP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3')polymer165067.31DNA molecule
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G
(A)
4-amino-1-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-onenon-polymer483.21Chemie (HF4)
8H
(A)
waterwater18.01Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight199942.3
Non-Polymers*Number of molecules2
Total formula weight507.5
All*Total formula weight200449.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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