8K7R
Human Fc epsilon RI in complex with hIgE Fc (TMD disordered)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity immunoglobulin epsilon receptor subunit alpha | polymer | 280 | 32578.8 | 1 | UniProt (P12319) Pfam (PF13927) Pfam (PF13895) | Homo sapiens (human) | |
| 2 | B, C (E, F) | IgE Fc | polymer | 351 | 39236.1 | 2 | Homo sapiens (human) | ||
| 3 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 5 | F (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 6 | G, H (G, H) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 7 | I, J (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A: 1 - 257 (UniProt: P12319)
| PDB | External Database | Details |
|---|---|---|
| Glu 258 | - | expression tag |
| Asn 259 | - | expression tag |
| Leu 260 | - | expression tag |
| Tyr 261 | - | expression tag |
| Phe 262 | - | expression tag |
| Gln 263 | - | expression tag |
| Gly 264 | - | expression tag |
| Asp 265 | - | expression tag |
| Tyr 266 | - | expression tag |
| Lys 267 | - | expression tag |
| Asp 268 | - | expression tag |
| Asp 269 | - | expression tag |
| Asp 270 | - | expression tag |
| Asp 271 | - | expression tag |
| Lys 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 111051.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3565.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 115058.7 |
