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8K78

Crystal structure of cMET kinase domain bound by TPX-0022

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHepatocyte growth factor receptorpolymer30934842.31UniProt (P08581)
Pfam (PF07714)
In PDB
Homo sapiens (human)HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2AElzovantinibnon-polymer409.41Chemie (IYC)
3waterwater18.062Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34842.3
Non-Polymers*Number of molecules1
Total formula weight409.4
All*Total formula weight35251.7
*Water molecules are not included.

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PDB entries from 2024-08-07

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