8K78
Crystal structure of cMET kinase domain bound by TPX-0022
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hepatocyte growth factor receptor | polymer | 309 | 34842.3 | 1 | UniProt (P08581) Pfam (PF07714) | Homo sapiens (human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
| 2 | B (A) | Elzovantinib | non-polymer | 409.4 | 1 | Chemie (IYC) | |||
| 3 | C (A) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34842.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 409.4 | |
| All* | Total formula weight | 35251.7 |
