8K72
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((3-(phenylsulfonamido)propanoyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
3 | G, H, I (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | J (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | K (A) | 2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid | non-polymer | 385.4 | 1 | Chemie (VJF) | |||
6 | Q (A) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 40328.3 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1687.7 | |
All* | Total formula weight | 42016.0 |