8K71
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((2-((naphthalen-2-ylmethyl)sulfonyl)acetyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (human) | Factor inhibiting HIF-1,FIH-1,Hypoxia-inducible factor asparagine hydroxylase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 2-[(2~{Z})-2-[2-(naphthalen-2-ylmethylsulfonyl)ethanoylimino]-3-oxidanyl-1,3-thiazol-4-yl]ethanoic acid | non-polymer | 420.5 | 1 | Chemie (VIZ) | |||
| 4 | D, E, F, G, H... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 5 | L, M, N, O, P... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | S (A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40328.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1899.0 | |
| All* | Total formula weight | 42227.3 |
