8K4P
Cryo-EM structure of an active Kaposi's Sarcoma-Associated Herpesvirus-G Protein-Coupled Receptor (KSHV-GPCR) in complex with Gi protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1 |
| 2 | B (A) | G protein-coupled receptor | polymer | 294 | 33329.9 | 1 | UniProt (Q76SF8) Pfam (PF00001) UniProt (by SIFTS) (Q98146) | Human gammaherpesvirus 8 | |
| 3 | C (C) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40415.0 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 4 | D (G) | Guanine nucleotide-binding protein subunit gamma | polymer | 55 | 6089.0 | 1 | UniProt (A0A6P5CFI6) Pfam (PF00631) UniProt (by SIFTS) (P59768) | Homo sapiens (human) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117032.6 | |
| All* | Total formula weight | 117032.6 |
