8K4N
Structure of GPR34-Gi complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40445.1 | 1 | UniProt (P63096) Pfam (PF00503) In PDB | Homo sapiens (human) | |
| 2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 336 | 36956.4 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 53 | 5844.8 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (human) | G gamma-I |
| 4 | E | scFv16 | polymer | 246 | 26222.2 | 1 | synthetic construct | ||
| 5 | D | Probable G-protein coupled receptor 34 | polymer | 279 | 32332.9 | 1 | UniProt (Q9UPC5) Pfam (PF00001) In PDB | Homo sapiens (human) | |
| 6 | D | (2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic acid | non-polymer | 467.5 | 1 | Chemie (VF0) |
Sequence modifications
A: 1 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 141801.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 142268.8 |
