8K4F
DHODH in complex with compound A0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 367 | 39812.4 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B, I, L (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | C, M (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 4 | D (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 5 | E (A) | 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione | non-polymer | 158.1 | 1 | Chemie (OG6) | |||
| 6 | F, G, H (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | J, K (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | N (A) | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine | non-polymer | 360.4 | 1 | Chemie (FJW) | |||
| 9 | O (A) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 30 - 395 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Ser 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39812.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1899.5 | |
| All* | Total formula weight | 41711.9 |
