8K0M

Human collagen prolyl processing enzyme complex, P3H1/CRTAP/PPIB heterotrimer, bound to 2-oxoglutarate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Prolyl 3-hydroxylase 1	polymer	736	83485.7	1	UniProt (Q32P28) Pfam (PF23557) Pfam (PF13640)	Homo sapiens (human)	Growth suppressor 1,Leucine- and proline-enriched proteoglycan 1,Leprecan-1
2	B (B)	Cartilage-associated protein	polymer	442	50749.2	1	UniProt (O75718) Pfam (PF23557)	Homo sapiens (human)
3	C (C)	Peptidyl-prolyl cis-trans isomerase B	polymer	256	28669.6	1	UniProt (P23284) Pfam (PF00160)	Homo sapiens (human)	PPIase B,CYP-S1,Cyclophilin B,Rotamase B,S-cyclophilin,SCYLP
4	D, E, H, I (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	F (A)	FE (III) ION	non-polymer		55.8	1	Chemie (FE)
6	G (A)	2-OXOGLUTARIC ACID	non-polymer		146.1	1	Chemie (AKG)

Sequence modifications

B: 1 - 401 (UniProt: O75718)

PDB	External Database	Details
Ala 402	-	expression tag
Ala 403	-	expression tag
Ala 404	-	expression tag
Leu 405	-	expression tag
Glu 406	-	expression tag
Val 407	-	expression tag
Leu 408	-	expression tag
Phe 409	-	expression tag
Gln 410	-	expression tag
Gly 411	-	expression tag
Pro 412	-	expression tag
Ser 413	-	expression tag
Ala 414	-	expression tag
Trp 415	-	expression tag
Ser 416	-	expression tag
His 417	-	expression tag
Pro 418	-	expression tag
Gln 419	-	expression tag
Phe 420	-	expression tag
Glu 421	-	expression tag
Lys 422	-	expression tag
Gly 423	-	expression tag
Gly 424	-	expression tag
Gly 425	-	expression tag
Ser 426	-	expression tag
Gly 427	-	expression tag
Gly 428	-	expression tag
Gly 429	-	expression tag
Ser 430	-	expression tag
Gly 431	-	expression tag
Gly 432	-	expression tag
Ser 433	-	expression tag
Ala 434	-	expression tag
Trp 435	-	expression tag
Ser 436	-	expression tag
His 437	-	expression tag
Pro 438	-	expression tag
Gln 439	-	expression tag
Phe 440	-	expression tag
Glu 441	-	expression tag
Lys 442	-	expression tag

C: 1 - 216 (UniProt: P23284)

PDB	External Database	Details
Ala 217	-	expression tag
Ala 218	-	expression tag
Ala 219	-	expression tag
Glu 220	-	expression tag
Asn 221	-	expression tag
Leu 222	-	expression tag
Tyr 223	-	expression tag
Phe 224	-	expression tag
Gln 225	-	expression tag
Gly 226	-	expression tag
Asp 227	-	expression tag
Tyr 228	-	expression tag
Lys 229	-	expression tag
Asp 230	-	expression tag
His 231	-	expression tag
Asp 232	-	expression tag
Gly 233	-	expression tag
Asp 234	-	expression tag
Tyr 235	-	expression tag
Lys 236	-	expression tag
Asp 237	-	expression tag
His 238	-	expression tag
Asp 239	-	expression tag
Ile 240	-	expression tag
Asp 241	-	expression tag
Tyr 242	-	expression tag
Lys 243	-	expression tag
Asp 244	-	expression tag
Asp 245	-	expression tag
Asp 246	-	expression tag
Asp 247	-	expression tag
Lys 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	162904.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1086.8
All*	Total formula weight	163991.3

*Water molecules are not included.